HIGH YIELD-TYPE II DM Flashcards
1
Q
enigmatic; highly attributed to lifestyle, what type of DM?
A
type II DM
2
Q
T/F, genetic factors even more important than in type I?
A
T
3
Q
what are the 2 metabolic defects?
A
derangements in B cell secretion of insulin
insulin resistance
4
Q
what is the major pathogenesis of DM II?
A
genetic factors
metabolic defects
obesity
amylin
5
Q
decreased response of peripheral tissues to insulin is what type of resistant?
A
insulin resistance
6
Q
T/F, insulin secretory defects w/o B-cell loss?
main cause?
what are the distinct defects?
A
T, doesnt fall in as 1 or 2; can be either
genetic
- autosomal dominant, monogenic defect with high penetrance
- early onset
- -impaired B cell function
- -normal weight
- -lack of insulin resistance
- -lack of GAD antibodies
severe insulin deficiency
mild chronic hyperglycemia
