HIGH YIELD-MALIGNANT

Question 1

most common liver tumor in pediatric population

90% occur before age 5

not assoc with cirrhosis
-primitive hepatocytes

tx: surgery, chemo, transplant

Answer 1

hepatoblastoma

Question 2

most common sarcoma in the liver?

highly aggressive neoplasm

associations: vinyl chloride, arsenic, thorotrast, androgenic steroids, cirrhosis

Answer 2

angiosarcoma

Question 3

roughly 5% of all cancers
more common in males

more than 85% of cases occur in countries with high rates of HBV

etiology:
viral (HBV/HCV)
chronic alcohol abuse

pain, jaundice, malaise, and weight loss

Answer 3

hepatocellular carcinoma

Question 4

less than 1/100,000 per year in the US; no gender or race predilection

risk factors:
primary sclerosing cholangitis

thorotrast exposure

liver fluke (parasite)
-opisthorchis sinesis

Answer 4

cholangiocarcinoma

Question 5

far more common than primary liver tumors

• common metastasis:breat, colon, lung
• -presents with multiple lesions

Answer 5

metastasic neoplasm