OTHER NEOPLASTIC PANCREAS Flashcards
proliferation of ductal epithelium in papillary formation with mucin production
M>F, 60+ y/o
head of pancreas
intraductal tumors
gross path of intraductal tumor?
variable ductal dilatation
thick mucus
histology of intraductal tumor?
papillary fronds of mucin filled epithelial cells
no ovarian like stroma
what are the other intraductal Tumors?
mucinous cystic neoplasm
intraductal papillary mucinous neoplasm
this other intraductal tumor?
F>M, 40-50
tail of pancreas
ovarian like stroma
not in duct system
mucinous cystic neoplasm
this other intraductal tumor?
M>F; 60-70s
head of pancreas
no ovarian like stroma
within duct system
intraductal papillary mucinous neoplasm
what is this tumor?
1-2% of pancreatic carcinoma
M>F, 60-70 y/o
hyper secretion of lipase
-subcutaneous fat necrosis, polyarthralgia
early metastasis to liver and lymph nodes
acinar cell tumors
what is this tumor?
75 total cases reported
most common pediatric pancreas tumor
good prognosis with surgery and chemotherapy
histology: rosette like structures, squamous corpuscles
pancreatoblastoma
what is this tumor?
5-8% of all pancreatic Tumors, found at autopsy
80% occur in MEN1 syndrome
if less than <2 cm, low risk of malignancy
90% of insulinomas are benign
-50-70% of others malignant
endocrine tumors
what type of endocrine tumor?
refractory hypoglycemia due to increased insulin secretion
confusion sweating nervousness due to hypoglycemia high insulin levels solitary and benign usually < 2 cm in size 30% of MEN1 tumors
insulinomas
what type of endocrine tumor?
arises in pancreas, duodenum, peripancreatic tissue
increased gastric acid secretion
-95% have duodenal ulcers
-zollinger Ellison syndrome
over half metastasized at presentation
tx: resect and block acid with PPI
50% of MEN1 tumors
gastrinomas
endocrine tumors can be?
insulin
glucagon
gastrin
