INFLAMMATORY DISORDERS-CHRONIC PANCREATITIS Flashcards
1
Q
progressive, inflammatory disease which can result in permanent and progressive impairment of function-irreversible changes to architecture
A
chronic pancreatitis
2
Q
T/F, can have intermittent acute attacks?
A
T
3
Q
major predispositions?
A
M>F
H/O gallstones
smoking
alcohol
4
Q
signs and symptoms?
A
elevated amylase during attack focal calcifications weight loss chronic abdominal pain high degree of suspicious
5
Q
what does pathology look like?
A
focal, diffuse, segmental
hard and fibrotic
dilatation and distortion of ducts
obstruction by calcification
6
Q
what does the histology look like?
A
loss of acinar and ductal tissue
fibrosis
ductal metaplasia
preservation of normal lobular architecture
