HIGH YIELD Flashcards

1
Q

what are the primary deficiencies?

A

dietary inadequacies

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2
Q

what are the secondary deficiencies?

A

malabsorption
impaired nutrition
excess nutrient loss
increased need for nutrietns

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3
Q

nutritional diseases affect affluent societies how?

A
ignorance
poverty
chronic alcoholism
acute and chronic diseases
self-imposed dietary restrictions
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4
Q

name it:

severe protein calorie malnutrition
amenorrhea
cold intolerance, bradycardia, hair and skin changes 
anemia
osteoporosis 

hypoalbuminemia
lymphopenia
decrease thyroid hormone
decrease GnRH, LH, FSH

increased risk of sudden death

A

anorexia nervosa

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5
Q

not enough adipose tissue thus affecting menstruation and ovulation

decrease GnRH, LH, FSH

A

amenorrhea

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6
Q

binging followed by induced vomiting

amenorrhea/menstrual irregularities
electrolyte abnormalities
pulmonary aspiration of gastric contents (not severe cachexia)

A

bulimia

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7
Q

what is the percent increase that is felt to impart a health risk?

A

20% increase

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8
Q

this regulates food intake as well as energy expenditure?

what are the obesity genes identified?

A

lipostat

LEP gene, leptin is the product

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9
Q

what neurohumoral mechanisms affect energy balance?

A
peripheral (afferent) system
arcuate nucleus (hypothalamus)
-leptin
-adiponectin
-insulin
-peptide YY

arcuate nucleus (hypothalamus), efferent sys

  • POMC/CART
  • NPY/AgRP
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10
Q

these neurons activate efferent neurons that enhance energy expenditure and weightloss?

A

POMC/CART

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11
Q

neurons activate efferent neurons that promote food intake & weight gain?

A

NPY/AgRP

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12
Q

what are the fat accumulation measurements?

A

body mass index
skinfold measurements
various body circumferences

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13
Q

body mass index (BMI)

18.5-25 kg/m2
25-30 kg/m2
>30 kg/m2

A

normal
overweight
obese

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14
Q

what type of distribution of fat has a higher risk for several diseases?

A

central (visceral) obesity

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15
Q

complications of obesity?

A
type II DM
hyperlipidemia
cancers
steatohepatitis
cholelithiasis
hypoventilation syndrome
degenerative joint disease
increased markers of infl
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16
Q

what are the 2 main protein compartments in the body?

A

somatic protein compartment-skeletal muscle
measurement: reduced circumference of the mid-arm***

visceral protein compartment-visceral organs like the liver
measurement: serum albumin, total protein, and transferrin

17
Q

name this disease?

results from a diet deficient in total calories

proteins, fats, carbs fall to 60% of normal

what protein compartments are broken down?

A

marasmus

somatic protein compartment with relative sparing of visceral protein-muscle wasting

18
Q

major clinical features/morphology of marasmus?

A
clinical features
muscle atrophy***
loss of subcutaneous fat
stunted growth
alerted and hungry

morphology
growth failure
loss of body fat
hypoplastic bone marrow

19
Q

name this disease?

deficient of protein and high in carbs

loss of protein in the visceral compartment

A

kwashiorkor

20
Q

major clinical features/morphology of kwashiokor?

A
apathy
generalized edema
skin and hair changes
-flag sign (pigment loss)
-dermatosis

enlarged fatty liver
generalized visceral atrophy
thymic atrophy

21
Q

name this disease?

common in chronically ill or hospitalized patients

cancer cachexia attribute to secondary PEM

A

secondary PEM