Chapter 9: Vitamin B7 (Biotin) Flashcards
other names:
anti-egg white injury factor
bios i
vitamin h
coenzyme r
biotin
biotin - chemistry
-sulfur-containing vitamin
-crystalline in its free form
-
biotin - chemistry
stable to (3)
heat, light, and acids
biotin - chemistry
unstable in (2)
alkali and oxidation
biotin - chemistry
produced by intestinal bacteria in the form of _____, a biologically active derivative; combined with the amino acid lysine
biocytin
biotin - chemistry
inactivated by _____, protein in raw egg whites
avidin
biotin - absorption, transport, and utilization
most absorption of biotin takes place in the upper portion of the _____ requiring a sodium-activated system
small intestine
biotin - function
converts pyruvate to oxaloacetate; gluconeogenesis
pyruvate decarboxylase
biotin - function
forms malonyl coa from acetate: fatty acid synthesis
acetyl coa carboxylase
biotin - function
converts propionate to succinate: amino acid metabolism
propionyl coa carboxylase
converts beta mcc to beta-methylglutaconyl coa: amino acid metabolism
beta-methylcrotonyl coa
biotin - function
participates in the _____ of aspartic acid, threonine, and serine
deamination
biotin - function
synthesis of _____ and _____
pancreatic amylase and nicotinic acid
biotin - function
plays a role in _____ formation
antibody formation
biotin - function
involved in many cellular reactions, particularly in fat and chon metabolism of hair roots, fingernails, and skin
-
biotin - deficiency
is rare; results from a rare genetic deficiency in _____, enzyme in the gut mucosa that can occur in about 1 to 40,000 infants
biotinidase
biotin - deficiency
biotinidase can also occur in individuals who consume _____ (6 per day) over many months because these contain a protein called avidin that binds biotin making it unavailable for utilization
raw egg whites
biotin - recommended intake
for conditions with: achlorydia, alcoholism, excessive egg white intake, sulfonamide therapy pregnancy and lactation, epileptics, and elderly
increased biotin intake
egg yolk, kidney, liver, milk, molasses, and yeast
biotin food sources