Chapter 10: Micromineral (Iodine) Flashcards

1
Q

required as a component of thyroid hormone, thyroxine (t4) and triiodothyronine (t3)

A

iodine

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2
Q

2 thyroid hormones

A

thyroxine; triiodothyronine

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3
Q

thyroid hormone (t4)

A

thyroxine

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4
Q

thyroid hormone (t3)

A

triiodothyronine

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5
Q

dietary iodine is in the form of

A

iodide

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6
Q

iodine - functions

a part of the _____

essential in regulating body’s growth, development, and metabolic rate

A

thyroid hormone

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7
Q

iodine - functions

_____ and _____ are required for normal energy metabolism, thermoregulation, and intermediary metabolism

A

thyroxine and triiodothyronine

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8
Q

iodine - functions

essential in the conversion of _____ to vitamin a

A

carotene

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9
Q

iodine - functions

protein synthesis, carbohydrate production, rbc production, nerve muscle function

A

-

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10
Q

iodine - absorption and metabolism

iodine is absorbed mainly in the _____, distributed in the extracellular fluids

A

small intestine

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11
Q

iodine - absorption and metabolism

reduced first to the absorbable _____; absorbed iodide is converted to iodine before it enters the circulatory system

A

iodide

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12
Q

iodine - absorption and metabolism

1/3 of the absorbed iodide in the blood is taken up by the _____ for synthesis of the thyroid hormones thyroxine (t4) and triiodothyronine (t3)

A

thyroid gland

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13
Q

iodine - absorption and metabolism

t3 and t4 circulate in the bloodstream bound to thyroxine binding globulin, prealbumin, and albumin

_____ is biologically more potent than _____

A

t3; t4

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14
Q

iodine - absorption and metabolism

the release of the t3/t4 by the thyroid is usually at a ratio of _____

this ratio is decreased when there is lack of iodine

A

20/1

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15
Q

iodine - absorption and metabolism

the rest of the iodide is excreted in the _____, some amounts are lost via the skin and feces

A

urine

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16
Q

iodine - absorption and metabolism

the metabolism of iodine occurs under the _____

A

hormonal feedback control

17
Q

iodine - absorption and metabolism

the uptake, synthesis, and release of iodine by the thyroid gland is stimulated by _____ released by the anterior pituitary gland

A

thyroid stimulating hormone

18
Q

iodine - interrelationship with other nutrients

from cabbage, kale, cauliflower, broccoli, turnip, brussel sprouts, and mustard greens

are substances that interferes with iodine metabolism inhibiting hormogenesis

A

goitrogens

19
Q

iodine - interrelationship with other nutrients

the goitrogens that affect iodide uptake by the thyroid glans, organification of the iodide or hormone release from the thyroid cells:

halide ions: bromide (br)
astatide (at-)
thiocyanate (SCN-)

A

-

20
Q

iodine - interrelationship with other nutrients

cassava contains _____ with thiocyanates as metabolited

A

cyanogen glucosides

21
Q

iodine - food sources

iodized salt, seafoods, seaweeds

A

iodine

22
Q

iodine - deficiency

most common forms of iodine deficiency are: _____ and _____

A

endemic goiter and cretinism

23
Q

iodine - deficiency

lack of iodine results in an enlargement of the _____ (goiter)

A

thyroid gland

24
Q

iodine - deficiency

enlargement of thyroid gland is due to over stimulation of the thyroid by _____ and _____, which are present in increased levels in an attempt to produce more circulating t3 and t3

A

TRF and TSH
thyrotropin-releasing factor;
thyroid-stimulating hormone

25
Q

iodine - deficiency

developmental defect in infants characterized by a dry thick skin, puffy face, and eyelids, enlarge tongue, husky voice, decreased reproductive ability, and mental retardation

A

cretinism

26
Q

iodine - toxicity

also known as Grave’s disease or exophthalmic goiter

increased basal metabolism, goiter, and disturbances in the autonomic nervous systems causing hyper irritability and increased creatinine metabolism

A

hyperthyroidism

27
Q

hyperthyroidism is also known as

A

grave’s disease or exophthalmic goiter

27
Q

iodine - deficiency

severe iodine deficiency can produce _____ which is characterized by a dry, waxy type swelling, with abnormal deposits of mucoproteins under the skin

A

myxedema

28
Q

iodine - recommended intake

for infants to children (0-5 years old) both male and female

A

90 ug

29
Q

iodine - recommended intake

for children (6-12 years old) both male and female

A

120 ug

30
Q

iodine - recommended intake

for children and adults (13->70 years old) both male and female

A

150 ug

31
Q

iodine - recommended intake

for pregnant and lactating

A

150 +100

32
Q

iodine - recommended intake

the recommended intake for adult corresponds to the intake necessary to maintain _____ level above the critical limit likely to be associated with the onset of goiter

it corresponds to the daily iodine urinary excretion of _____ ug/L

A

plasma iodide; 100 ug/L

33
Q

iodine - recommended intake

pregnant and lactating mothers

A

at risk of developing iodine deficiency