Chapter 10: Micromineral (Manganese) Flashcards
cofactor for a number of enzymes involved in urea, cholesterol fatty acid biosynthesis, and in cho, chon, and energy metabolism
*cofactor action is not specific
manganese
body contains _____ concentrated Mn in the liver, pancreas, skin, muscles, bones
29 mg
manganese - functions
- required by mitochondrial superoxide dismutase, catalyzes the conversion of superoxide to _____
the HOOH formed by superoxide is decomposed by catalse
hydrogen peroxide
manganese - functions
- as a cofactor, it is involved in _____ and _____ metabolism
glucose and fatty acid
manganese - functions
- needed in utilization of
thiamin
manganese - functions
- needed in the release of _____ from the liver
lipid
manganese - functions
- _____ synthesis
urea
manganese - functions
- amino acid interconversion
-
manganese - functions
required for the normal development of _____ and _____
skeleton and connective tissues
manganese - absorption and metabolism
catabolism by _____
manganese-binding protein transferrin
manganese - absorption and metabolism
primary route of excretion
bile
manganese - absorption and metabolism
99% of the body’s losses of Mn are
fecal
manganese - interrelationship with other nutrients
Mn absorption decreased with high intakes of _____
fe or iron
manganese - interrelationship with other nutrients
_____ and _____ may affect bioavailabity of Mn
calcium and zinc
manganese - deficiency
does not usually develop unless the mineral is deliberately eliminated in the diet
-