Chapter 9: Fat-soluble Vitamins (Vitamin K) Flashcards
other names:
-anti-hemorrhagic vitamin/factor
-coagulation factor
-menadione
-phylloquinone
-papthoquinone
vitamin k
vitamin k - chemistry
belongs to a group of chemicals called _____. this includes phylloquinone and menaquinone
quinones
vitamin k1 is known as
phylloquinone
vitamin k2 is known as
menaquinone
phylloquinone or k1 is present in
plant foods
menaquinone or k2 is present in
animal tissues
vitamin k3
menadione
menaquinone or k2 is is synthesized by
intestinal bacteria
vitamin k - chemistry
vitamin k color
yellow
vitamin k - chemistry
is resistant in?
heat
vitamin k - chemistry
is easily destroyed by (4)
alkali, strong acid, light, and oxidizing agents
vitamin k - absorption, transport, utilization
phylloquinone is absorbed by _____
active transport
vitamin k - absorption, transport, utilization
menaquinone is absorbed by
passive transport
vitamin k - absorption, transport, utilization
absorbed in the _____, incorporated into chylomicrons, and is taken up by the liver
small intestinal wall cells
vitamin k - absorption, transport, utilization
incorporated into very low-density lipoproteins and eventually carried to the _____ by low-density lipoproteins
extrahepatic tissues
vitamin k - relationship with other nutrients
antagonistic effect of _____ (2), interferes with vitamin k absorption if excess
vitamin a and e
vitamin k - relationship with other nutrients
vitamin d functions are related to
calcium metabolism
vitamin k - relationship with other nutrients
vitamin k-dependent proteins are capable of
binding calcium
vitamin k - functions
essential for the synthesis of several proteins involved in blood-clotting, among them is _____, made by the liver as a precursor of the protein thrombin
prothrombin
vitamin k - functions
prothrombin is made by the??
liver
it is made by the liver as a precursor of the protein thrombin
prothrombin
vitamin k - functions
participates in the synthesis of a bone protein, most notably _____
osteocalcin
vitamin k - functions
needed in the _____ of certain glutamate residues allowing a firm binding of calcium
gamma-carboxylation
vitamin k - deficiency
refers to the delayed clotting time due fat malabsorption, loss or lack of microorganism which synthesize vitamin k
hemorrhagic disease
vitamin k - toxicity
condition brought about by the uncontrolled use of menadione,
hypervitaminosis k
vitamin k - toxicity
the synthetic vitamin k results in
_____ anemia (rbc hemolysis)
hemolytic anemia
vitamin k - toxicity
the synthetic vitamin k results in
accumulation of bilirubin in the blood
hyperbilirubinemia
vitamin k - toxicity
the synthetic vitamin k results in
wherein the bile pigment accumulates in the gray matter of the central nervous system leading to brain damage
kernicterus
vitamin k - recommended intake
for adults (19->70 y/o) males
61 ug
vitamin k - recommended intake
for adults (19->70 y/o) females
53 ug
vitamin k - recommended intake
at risk individuals are
-newborn infants
-those with renal insufficiency
-those being teated chronically with antibiotics
at risk individuals
vitamin k
green leafy vegetables (parsley, spinach, collard greens, and salad greens), cabbage, vegetable oils (soybean, canola, olive), cauliflower, carrots, tomatoes, egg yolk, pork liver, and seaweeds
vitamin k sources
