Chapter 9: Fat-soluble Vitamins (Vitamin K) Flashcards

1
Q

other names:
-anti-hemorrhagic vitamin/factor
-coagulation factor
-menadione
-phylloquinone
-papthoquinone

A

vitamin k

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2
Q

vitamin k - chemistry

belongs to a group of chemicals called _____. this includes phylloquinone and menaquinone

A

quinones

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3
Q

vitamin k1 is known as

A

phylloquinone

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4
Q

vitamin k2 is known as

A

menaquinone

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5
Q

phylloquinone or k1 is present in

A

plant foods

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6
Q

menaquinone or k2 is present in

A

animal tissues

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7
Q

vitamin k3

A

menadione

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8
Q

menaquinone or k2 is is synthesized by

A

intestinal bacteria

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9
Q

vitamin k - chemistry

vitamin k color

A

yellow

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10
Q

vitamin k - chemistry

is resistant in?

A

heat

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11
Q

vitamin k - chemistry

is easily destroyed by (4)

A

alkali, strong acid, light, and oxidizing agents

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12
Q

vitamin k - absorption, transport, utilization

phylloquinone is absorbed by _____

A

active transport

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13
Q

vitamin k - absorption, transport, utilization

menaquinone is absorbed by

A

passive transport

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14
Q

vitamin k - absorption, transport, utilization

absorbed in the _____, incorporated into chylomicrons, and is taken up by the liver

A

small intestinal wall cells

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15
Q

vitamin k - absorption, transport, utilization

incorporated into very low-density lipoproteins and eventually carried to the _____ by low-density lipoproteins

A

extrahepatic tissues

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16
Q

vitamin k - relationship with other nutrients

antagonistic effect of _____ (2), interferes with vitamin k absorption if excess

A

vitamin a and e

17
Q

vitamin k - relationship with other nutrients

vitamin d functions are related to

A

calcium metabolism

18
Q

vitamin k - relationship with other nutrients

vitamin k-dependent proteins are capable of

A

binding calcium

19
Q

vitamin k - functions

essential for the synthesis of several proteins involved in blood-clotting, among them is _____, made by the liver as a precursor of the protein thrombin

A

prothrombin

20
Q

vitamin k - functions

prothrombin is made by the??

A

liver

21
Q

it is made by the liver as a precursor of the protein thrombin

A

prothrombin

22
Q

vitamin k - functions

participates in the synthesis of a bone protein, most notably _____

A

osteocalcin

23
Q

vitamin k - functions

needed in the _____ of certain glutamate residues allowing a firm binding of calcium

A

gamma-carboxylation

24
Q

vitamin k - deficiency

refers to the delayed clotting time due fat malabsorption, loss or lack of microorganism which synthesize vitamin k

A

hemorrhagic disease

25
Q

vitamin k - toxicity

condition brought about by the uncontrolled use of menadione,

A

hypervitaminosis k

26
Q

vitamin k - toxicity

the synthetic vitamin k results in
_____ anemia (rbc hemolysis)

A

hemolytic anemia

27
Q

vitamin k - toxicity

the synthetic vitamin k results in
accumulation of bilirubin in the blood

A

hyperbilirubinemia

28
Q

vitamin k - toxicity

the synthetic vitamin k results in
wherein the bile pigment accumulates in the gray matter of the central nervous system leading to brain damage

A

kernicterus

29
Q

vitamin k - recommended intake

for adults (19->70 y/o) males

A

61 ug

30
Q

vitamin k - recommended intake

for adults (19->70 y/o) females

A

53 ug

31
Q

vitamin k - recommended intake

at risk individuals are
-newborn infants
-those with renal insufficiency
-those being teated chronically with antibiotics

A

at risk individuals

32
Q

vitamin k

green leafy vegetables (parsley, spinach, collard greens, and salad greens), cabbage, vegetable oils (soybean, canola, olive), cauliflower, carrots, tomatoes, egg yolk, pork liver, and seaweeds

A

vitamin k sources