Chapter 7: CHO - Metabolic Reactions (Glycogenolysis)

Question 1

refers to the intracellular breakdown of glycogen to form glucose or glucose 6-phosphate

Answer 1

glycogenolysis

Question 2

degradation of glycogen is stimulated by _____ in muscle and _____ in the liver via activation of adenylyl cyclase

Answer 2

adrenaline; glucagon

Question 3

increase levels of cAMP activates protein kinase A

protein kinase a activates _____ that releases glucose 1-phosphate units from glyccogen

Answer 3

glycogen phosphorylase

Question 4

in the liver, glucose can be produced from _____ via glucose 6-phosphate,

in the muscle, glucose 6-phosphate ic absent and the glucose 6-phosphate is channeled into _____ pathway for provision of energy

Answer 4

glucose 1-phosphate; glycolytic pathway

Question 5

tissue/organ involved in glycogenolysis

Answer 5

muscle and liver

Question 6

cell site of the reaction (glycogenolysis)

Answer 6

cytosol

Question 7

starting material of glycogenolysis

Answer 7

glycogen

Question 8

final product of glycogenolysis

Answer 8

glucose or glucose 6-phosphate

Question 9

glycogenolysis - summary of stages of reaction

1. _____ of the glycogen to cleave the alpha-14 glucosidic bond

Answer 9

phosphorolysis

Question 10

glycogenolysis - summary of stages of reaction

2. conversion of glucose 1-phosphate to glucose 6-phosphate by the enzyme ??

Answer 10

phosphoglucomutase

Question 11

glycogenolysis - summary of stages of reaction

3. hydrolysis of glucose 6-phosphate to glucose via the enzyme _____

Answer 11

glucose 6-phosphatase

Question 12

glycogenolysis is activated by the enzyme

Answer 12

glycogen phosphorylase

Question 13

glycogenolysisis regulated by (3)

Answer 13

low insulin and high glucagons, cAMP, calmodulin

Question 14

cAMP meaning

Answer 14

Cyclic adenosine monophosphate

Question 15

glycogenolysisis energetics

Answer 15

(glucose)n + h2o glucose n-1 + glucose

Question 16

net ATP (produced and used) is?

Answer 16

0