Chapter 7: CHO - Metabolic Reactions (Glycolysis) Flashcards

1
Q

reactions that involves the breaking down of molecules into smaller ones and yield energy

A

catabolism

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2
Q

uses energy to create larger molecules from small molecules

A

anabolism

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3
Q

the sum of all the chemical reactions, either catabolic or anabolic, that occur in living cells

A

metabolism

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4
Q

the degenerative pathway where glucose is converted to pyruvate

it is integrated to many biochemical processes

A

glycolysis

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5
Q

d-glucose is oxidized to _____ or _____

A

pyruvate or lactate

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6
Q

oxidation of d-glucose to pyruvate or lactate is linked to glycogen metabolism through

A

d-glucose 6 phosphate

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7
Q

-generating adenosine-triphosphate (ATP)
-producing pyruvate
-forming intermediate compounds for other metabolic processes such as: glycerol 3-phosphate (triglyceride and phospholipid biosynthesis); 2,3-diphosphoglycerate in erythrocytes; pyruvate for alanine synthesis; etc.

A

other functions of glycolysis

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8
Q

in the brain and erythrocytes

this enzyme involved enables them to utilize glucose even when it is present in low concentrations

A

hexokinase

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9
Q

in the liver

this reaction is catalyzed by _____ (_____)

liver acts as supplier of glucose when the supply is limited

A

glucokinase (hexokinase d)

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10
Q

tissues
involved with enzyme hexokinase

A

brain and erythrocytes

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11
Q

tissues involved in the catalyzation of glucokinase

A

liver

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12
Q
  1. processes involved

converted to fructose 6-phosphate and phosphorylated for a second time by phosphofructokinase, using ATP

A

glucose-6-phosphate

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13
Q
  1. processes involved

the resulting _____ is split into 2 interconvertible triose phosphates, glyceraldehydes 3-phosphates and dihydroxyacetone phosphate

A

fructose 1,6-biphosphate

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14
Q
  1. processes involved

the resulting fructose 1,6-biphosphate is split into 2 interconvertible triose phosphates,

A

glyceraldehydes 3-phosphates and dihydroxyacetone phosphate

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15
Q
  1. processes involved

a complex reaction follows, catalyzed by _____ in which glyceraldehyde 3-phosphate is oxidized using NAD+ as a coenzyme and inorganic phosphate as a second substrate to form 1,3-bisphosphoglycerate and NADH

A

glyceraldehydes 3-phosphate dehydrogenase

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16
Q
  1. processes involved

a complex reaction follows, catalyzed by glyceraldehydes 3-phosphate dehydrogenase in which glyceraldehyde 3-phosphate is oxidized using _____ as a coenzyme and _____ as a second substrate to form 1,3-bisphosphoglycerate and NADH

A

NAD+
inorganic phosphate

17
Q
  1. processes involved

a complex reaction follows, catalyzed by glyceraldehydes 3-phosphate dehydrogenase in which glyceraldehyde 3-phosphate is oxidized using NAD+ as a coenzyme and inorganic phosphate as a second substrate to form _____

A

1,3-bisphosphoglycerate and NADH

18
Q
  1. processes involved

subsequent reactions lead to the formation of _____, the phosphate that is readily transferable to ADP to yield ATP (another 2 molecules per glucose molecule). the enzyme is involved in pyruvate kinase

A

phosphoenolpyruvate

19
Q
  1. processes involved

subsequent reactions lead to the formation of phosphoenolpyruvate, the phosphate that is readily transferable to ADP to yield ATP (another 2 molecules per glucose molecule). the enzyme is involved in _____

A

pyruvate kinase

20
Q
  1. processes involved

the next energy yield in glycolysis starting with 1 molecule of glucose is _____ molecules of ATP

A

2 molecules of atp

21
Q
  1. processes involved

glycolysis involved at several sites, mechanism depends on the tissue involved

in the brain, skeletal muscle, and erythrocytes, glycolysis is _____

A

catabolic, energy-producing pathway

22
Q
  1. processes involved

glycolysis in involved at several sites, mechanism depends on the tissue involved

in the liver, it is a part of an overall _____

A

anabolic process, the synthesis of fatty acids from glucose

23
Q

tissues that catabolizes glycolysis pathway

A

brain, skeletal muscles, erythrocytes

24
Q

tissue that is involved in anabolic process

A

liver

25
Q

tissue/organ involved in glycolysis

A

liver, brain, muscles

26
Q

cell site of glycolysis reaction

A

cytosol (mitochondria)

27
Q

starting material (intermediate sources) for the synthesis of triacylglycerols from

A

glyceraldehyde 3-phosphate

28
Q

starting material (intermediate sources) for the synthesis of glycogen from

A

glucose 1-phosphate

29
Q

starting material (intermediate sources) for the synthesis of alanine from

A

pyruvate

30
Q

end product of this reaction is _____

A

pyruvate

31
Q

pyruvate is the precursor of the formation of

A

acetyl coenzyme A (CoA) or lactate

32
Q
  1. summary of the reaction

reaction start with the formation of

A

glucose-6 phosphate

33
Q
  1. summary of the reaction

splitting glucose-6 phosphate into

A

glyceraldehydes-3 phosphate

34
Q
  1. summary of the reaction

oxidation of _____ to _____

A

3-phosphoglyceraldehyade to pyruvate

35
Q

activators

when oxygen is adequate, glucose enters the _____, where it is converted to carbon dioxide and water

A

tricarboxylic acid (TCA) cycle

36
Q

activators

when oxygen is adequate, glucose enters the tricarboxylic acid (TCA) cycle, where it is converted to _____ and _____

A

carbon dioxide and water

37
Q

regulators

regulation is done by availability of _____, relative concentration of NAD+/NADH, H+, and enzymatic activity of the hexokinase, phosphofructokinase, and pyruvate kinase

A

substrates

38
Q

glycolysis provides how many ATP (net ATP)

A

2

39
Q

NET

A

2 ATP
2 NADH
2 pyruvate