Chapter 7: CHO - Metabolic Reactions (Glycolysis) Flashcards

1
Q

reactions that involves the breaking down of molecules into smaller ones and yield energy

A

catabolism

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2
Q

uses energy to create larger molecules from small molecules

A

anabolism

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3
Q

the sum of all the chemical reactions, either catabolic or anabolic, that occur in living cells

A

metabolism

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4
Q

the degenerative pathway where glucose is converted to pyruvate

it is integrated to many biochemical processes

A

glycolysis

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5
Q

d-glucose is oxidized to _____ or _____

A

pyruvate or lactate

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6
Q

oxidation of d-glucose to pyruvate or lactate is linked to glycogen metabolism through

A

d-glucose 6 phosphate

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7
Q

-generating adenosine-triphosphate (ATP)
-producing pyruvate
-forming intermediate compounds for other metabolic processes such as: glycerol 3-phosphate (triglyceride and phospholipid biosynthesis); 2,3-diphosphoglycerate in erythrocytes; pyruvate for alanine synthesis; etc.

A

other functions of glycolysis

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8
Q

in the brain and erythrocytes

this enzyme involved enables them to utilize glucose even when it is present in low concentrations

A

hexokinase

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9
Q

in the liver

this reaction is catalyzed by _____ (_____)

liver acts as supplier of glucose when the supply is limited

A

glucokinase (hexokinase d)

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10
Q

tissues
involved with enzyme hexokinase

A

brain and erythrocytes

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11
Q

tissues involved in the catalyzation of glucokinase

A

liver

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12
Q
  1. processes involved

converted to fructose 6-phosphate and phosphorylated for a second time by phosphofructokinase, using ATP

A

glucose-6-phosphate

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13
Q
  1. processes involved

the resulting _____ is split into 2 interconvertible triose phosphates, glyceraldehydes 3-phosphates and dihydroxyacetone phosphate

A

fructose 1,6-biphosphate

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14
Q
  1. processes involved

the resulting fructose 1,6-biphosphate is split into 2 interconvertible triose phosphates,

A

glyceraldehydes 3-phosphates and dihydroxyacetone phosphate

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15
Q
  1. processes involved

a complex reaction follows, catalyzed by _____ in which glyceraldehyde 3-phosphate is oxidized using NAD+ as a coenzyme and inorganic phosphate as a second substrate to form 1,3-bisphosphoglycerate and NADH

A

glyceraldehydes 3-phosphate dehydrogenase

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16
Q
  1. processes involved

a complex reaction follows, catalyzed by glyceraldehydes 3-phosphate dehydrogenase in which glyceraldehyde 3-phosphate is oxidized using _____ as a coenzyme and _____ as a second substrate to form 1,3-bisphosphoglycerate and NADH

A

NAD+
inorganic phosphate

17
Q
  1. processes involved

a complex reaction follows, catalyzed by glyceraldehydes 3-phosphate dehydrogenase in which glyceraldehyde 3-phosphate is oxidized using NAD+ as a coenzyme and inorganic phosphate as a second substrate to form _____

A

1,3-bisphosphoglycerate and NADH

18
Q
  1. processes involved

subsequent reactions lead to the formation of _____, the phosphate that is readily transferable to ADP to yield ATP (another 2 molecules per glucose molecule). the enzyme is involved in pyruvate kinase

A

phosphoenolpyruvate

19
Q
  1. processes involved

subsequent reactions lead to the formation of phosphoenolpyruvate, the phosphate that is readily transferable to ADP to yield ATP (another 2 molecules per glucose molecule). the enzyme is involved in _____

A

pyruvate kinase

20
Q
  1. processes involved

the next energy yield in glycolysis starting with 1 molecule of glucose is _____ molecules of ATP

A

2 molecules of atp

21
Q
  1. processes involved

glycolysis involved at several sites, mechanism depends on the tissue involved

in the brain, skeletal muscle, and erythrocytes, glycolysis is _____

A

catabolic, energy-producing pathway

22
Q
  1. processes involved

glycolysis in involved at several sites, mechanism depends on the tissue involved

in the liver, it is a part of an overall _____

A

anabolic process, the synthesis of fatty acids from glucose

23
Q

tissues that catabolizes glycolysis pathway

A

brain, skeletal muscles, erythrocytes

24
Q

tissue that is involved in anabolic process

25
tissue/organ involved in glycolysis
liver, brain, muscles
26
cell site of glycolysis reaction
cytosol (mitochondria)
27
starting material (intermediate sources) for the synthesis of triacylglycerols from
glyceraldehyde 3-phosphate
28
starting material (intermediate sources) for the synthesis of glycogen from
glucose 1-phosphate
29
starting material (intermediate sources) for the synthesis of alanine from
pyruvate
30
end product of this reaction is _____
pyruvate
31
pyruvate is the precursor of the formation of
acetyl coenzyme A (CoA) or lactate
32
1. summary of the reaction reaction start with the formation of
glucose-6 phosphate
33
2. summary of the reaction splitting glucose-6 phosphate into
glyceraldehydes-3 phosphate
34
3. summary of the reaction oxidation of _____ to _____
3-phosphoglyceraldehyade to pyruvate
35
activators when oxygen is adequate, glucose enters the _____, where it is converted to carbon dioxide and water
tricarboxylic acid (TCA) cycle
36
activators when oxygen is adequate, glucose enters the tricarboxylic acid (TCA) cycle, where it is converted to _____ and _____
carbon dioxide and water
37
regulators regulation is done by availability of _____, relative concentration of NAD+/NADH, H+, and enzymatic activity of the hexokinase, phosphofructokinase, and pyruvate kinase
substrates
38
glycolysis provides how many ATP (net ATP)
2
39
NET
2 ATP 2 NADH 2 pyruvate