Chapter 10: Micromineral (Copper) Flashcards
a cofactor for a wide range of enzymes; an essential element
copper
occurs in the cuprous and cupric form
copper
cu+
cuprous
cupric
cu2+
involved in oxidation-recution reactions
copper
body’s copper content ranges from
5-120 mg
highest concentration of the mineral is in the _____
liver
lesser amounts of the mineral is in the _____ (4)
heart, kidneys, spleen, and brain
copper in the blood and tissues is normally bound to
proteins
copper - functions
essential as an activator of key enzymatic reactions
copper
copper - functions
catalyzed the oxidation of the cytochrome C, a and a3 complex by oxygen in the respiratory chain
cytochrome c oxidase
copper - functions
(a) oxidizes ferrous ions to ferric ions; (b) transports copper to tissue sites; (c) acts as a scavenger of free radicals and superoxide ions
ceruloplasmin
copper - functions
toxic oxygen removal
superoxide dismutase
copper - functions
collagen synthesis
lysyl oxidase
copper - functions
neurotransmitter synthesis
dopamine betahydroxylases
copper - functions
melanin synthesis
tyrosine oxidase
copper - absorption and metabolism
about 20-45% of dietary copper is absorbed from all parts of the GI tract, including the _____ (2)
stomach and large intestine
copper - absorption and metabolism
bind with proteins such as _____, which slows down Cu absorption in the blood
metallothionein
copper - absorption and metabolism
removed from the plasma by the _____ from where it is either excreted into the bile or used in the synthesis of ceruloplasmin, the copper-containing enzyme
liver
the copper containing enzyme
ceruloplasmin
copper - absorption and metabolism
released from the liver under the control of the _____
body utilized some of the plasma copper in the synthesis of superoxide dismutase in the bone marrow
adrenal gland
copper - absorption and metabolism
copper is excreted in both the
feces and urine
copper - interrelationship with other nutrients
high intake of _____ or _____ decreases the absorption of copper
iron or vitamin c
copper - interrelationship with other nutrients
decreases copper absorption
zinc