Chapter 9: Fat-soluble Vitamins (Vitamin A) Flashcards

1
Q

other names

retinoic acid
retinal
retinol
dehydroretinol
anti-infective vitamin

A

vitamin a

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2
Q

vitamin a - chemistry

stable to _____ (ordinary cooking temp), _____, and _____

A

heat, acid, alkali

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3
Q

vitamin a - chemistry

destroyed by _____ and _____ (when become rancid) or light

A

oxidation and destruction

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4
Q

vitamin a - chemistry

exists in 3 forms that are found in animal tissues

A

retinol, retinal, or retinaldehyde and reitnoic acid

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5
Q

vitamin a - chemistry

are formed when retinol combines with an organis acid

A

retinyl esters

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6
Q

vitamin a - chemistry

retinyl esters, retinol, and retinal are incovertible; all forms can be converted to retinol acid, a “_____”

A

terminal product

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7
Q

vitamin a - chemistry

are precursors of vitamin a and occur in 2 structural forms

A

carotenes

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8
Q

vitamin a - chemistry

carotenes occur in 2 structural forms that are present in plants (as provitamin, carotenoid precursor)

A

alpha carotene and beta carotene

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9
Q

vitamin a - chemistry

can undergo oxidative cleavage to 2 molecules of retinol

A

beta carotene

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10
Q

vitamin a - chemistry

_____ refers to a biologically active form. found in the animal foods

A

retinol esters

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11
Q

vitamin a - chemistry

_____ is the unit of measure

A

retinol equivalent (re)

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12
Q

vitamin a - chemistry

_____ and united states pharmacopeia units are used to measure vitamin a activity

A

international units (iu)

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13
Q

vitamin a - chemistry

RE = 1 ug retinol (_____ IU)

A

3.33

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14
Q

vitamin a - chemistry

1 RE = _____ beta carotene (10 IU)

A

6 ug

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15
Q

vitamin a - chemistry

1 RE = _____ other carotenoids

A

12 ug

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16
Q

vitamin a - absorption, transport, and utilization

_____ and _____ are the preformed vitamin a (easily absorbed) because it can be metabolized directly into compounds that exert biological effect of vitamin a

A

retinol and retinyl esters

17
Q

vitamin a - absorption, transport, and utilization

are produced only by plants, and they function as accessory light-gathering pigments that enhance photosynthesis efficiency

A

carotenoids

18
Q

vitamin a - absorption, transport, and utilization

carotenoids are the common dietary source, however, they are absorbed at much _____ rates

A

slower rates

19
Q

vitamin a - absorption, transport, and utilization

retinol from food can be absorbed as such by the _____

A

intestinal wall cells

20
Q

vitamin a - absorption, transport, and utilization

are hydrolyzed to free retinol and an organic acid

A

retinyl esters

21
Q

vitamin a - absorption, transport, and utilization

absorption if facilitated by

A

bile

22
Q

vitamin a - absorption, transport, and utilization

_____ carotene are needed to produce the vitamin a activity of 1 ug retinol

A

6 ug

23
Q

vitamin a - absorption, transport, and utilization

is the predominant retinyl ester in food

A

retinyl palmate

24
Q

_____% of performed dietary vitamin a is absorbed

A

75%

25
Q

vitamin a - absorption, transport, and utilization

dietary beta carotene and other carotenoids, _____ is absorbed

A

5-50%

26
Q

vitamin a - absorption, transport, and utilization

stored in the _____ (90%) and _____

A

liver; adipose tissue

27
Q

vitamin a - absorption, transport, and utilization

incorporated into the _____ for transport through the _____

A

chylomicrons; lymphatic system

28
Q

vitamin a - absorption, transport, and utilization

cellular RBP and cellular retinoic acid-binding protein attach to retinol and retinoic acid, respectively; transfer to cell nucleus where they can effect gene expression

A

intracellular retinol-binding proteins

29
Q

vitamin a - absorption, transport, and utilization

storage of vitamin a occurs in the liver as _____

A

retinyl ester

30
Q

vitamin a - absorption, transport, and utilization

when in need, it is released from the liver, transported to the blood by forming a complex with a transport protein called _____

A

RBP

31
Q

vitamin a - absorption, transport, and utilization

the conversion of retinol to retinoic acid is _____

A

irreversible