9.8 - Lung cancer

Question 1

what can produce a coin lesion?

Answer 1

• lung cancer
• granuloma (TB, fungus, histo)
• bronchial hamartoma

Question 2

bronchial hamartomas are composed of _______ and ________

Answer 2

lung tissue and cartilage

Question 3

what are the subtypes of non-small cell lung cancer (85%)?

Answer 3

• adenocarcinoma (40%)
• squamous cell carcinoma (30%)
• large cell carcinoma (10%)
• carcinoid (5%)

Question 4

pleural involvement is classically seen with what subtype of non-small cell lung cancer?

Answer 4

adenocarcinoma

Question 5

histology: keratin pearls, intercellular bridges

Answer 5

squamous cell carcinoma

Question 6

histology: columnar cells that grow along preexisting bronchioles and alveoli

Answer 6

bronchioloalveolar carcinoma

Question 7

which type of lung cancer arises from club cells?

Answer 7

bronchioloalveolar carcinoma

Question 8

carcinoid tumors stain positive for __________

Answer 8

chromogranin

Question 9

bronchioloalveolar carcinoma arises from what cell type?

Answer 9

club cells

Question 10

chromogranin is positive in what type of lung cancer?

Answer 10

carcinoid

Question 11

what are the most common sources for metastatic lung cancer?

Answer 11

• breast

- colon

Question 12

which lung cancers are located peripherally?

Answer 12

• adeno
• bronchioloalveolar
• carcinoid (sometimes)

Question 13

“cannon ball” nodules on imaging - diagnosis?

Answer 13

metastatic lung cancer

Question 14

which lung cancer produces PTHrP?

Answer 14

squamous cell carcinoma

Question 15

histology: well differentiated neuroendocrine cells

Answer 15

carcinoid tumor

Question 16

a pancoast tumor can cause __________

Answer 16

horner syndrom:

• ptosis
• miosis
• anhydrosis

Question 17

what is the unique site of distant lung metastases?

Answer 17

adrenal gland