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Pathoma > 7.1 - Vasculitis > Flashcards

7.1 - Vasculitis Flashcards

1
Q

is temporal arteritis granulomatous or necrotizing?

A

granulomatous

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2
Q

biopsy of temporal arteritis reveals inflamed vessel wall with giant cells and fibrosis of which layer?

A

intima

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3
Q

what is the treatment for giant cell arteritis? what is the consequence of no treatment?

A
  • corticosteroids

- blindness

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4
Q

is takayasu arteritis granulomatous or necrotizing?

A

granulomatous

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5
Q
  • visual and neuro symptoms
  • weak or absent pulse
  • elevated ESR

diagnosis? treatment?

A
  • takayasu arteritis

- corticosteroids

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6
Q

is polyarteritis nodosa granulomatous or necrotizing?

A

necrotizing

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7
Q

which organ is spared in polyarteritis nodosa?

A

lungs

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8
Q
  • HTN
  • abdominal pain with melena
  • neuro disturbances
  • skin lesions

diagnosis? treatment?

A
  • polyarteritis nodosa

- corticosteroids and cyclophosphamide

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9
Q

what serum marker is frequently seen with polyarteritis nodosa?

A

serum HBsAg

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10
Q
  • lesions at various stages
  • transmural inflammation with fibrinoid necrosis
  • string of pearls appearance on imaging
A

polyarteritis nodosa

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11
Q
  • fever
  • conjunctivitis
  • erythematous rash of palms and soles
  • enlarged cervical nodes
A

kawasaki disease

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12
Q

coronary artery involvement in kawasaki disease leads to increased risk of what two outcomes?

A
  1. aneurysm with rupture

2. thrombosis with myocardial infarction

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13
Q

what is the treatment for kawasaki disease?

A
  • aspirin

- IVIG

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14
Q

is buerger disease necrotizing or granulomatous?

A

necrotizing

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15
Q

necrotizing granulomatous vasculitis involving nasopharynx, lungs, and kidneys

A

wegener granulomatosis

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16
Q
  • middle aged male
  • sinusitis / nasopharyngeal ulceration
  • hemoptysis with bilateral nodular lung infiltrates
  • hematuria
  • rapidly progressing glomerulonephritis
A

wegener granulomatosis

17
Q

is wegener granulomatosis positive for c-ANCA or p-ANCA?

A

c-ANCA

18
Q

what is the treatment for wegener granulomatosis?

A

cylcophosphamide and steroids

19
Q

is wegener granulomatosis granulomatous or necrotizing?

A

necrotizing and granulomatous

20
Q

what makes microscopic polyangiitis different from wegener granulomatosis?

A

microscopic polyangiitis does NOT have nasopharyngeal involvement (nor does it have granulomas)

21
Q

is microscopic polyangiitis granulomatous or necrotizing?

A

necrotizing

22
Q

is microscopic polyangiitis positive for c-ANCA or p-ANCA?

A

p-ANCA

23
Q
  • asthma
  • peripheral eosinophilia
  • p-ANCA positive
A

churg strauss

24
Q

is churg strauss granulomatous or necrotizing?

A

necrotizing and granulomatous (with eosinophils)

25
Q

is churg strauss positive for c-ANCA or p-ANCA?

A

p-ANCA

26
Q

henoch schonlein purpura is a vasculitis due to immune complex deposition of Ig___

A

IgA

27
Q
  • palpable purpura on buttocks and legs
  • GI pain and bleeding
  • hematuria (IgA nephropathy)
A

henoch schonlein purpura

Pathoma (120 decks)

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