15.5 - Hypothyroidism Flashcards
1
Q
- mental retardation
- short stature (skeletal abnormalities)
- coarse facial features
- enlarged tongue
- umbilical hernia
A
cretinism
2
Q
what are the causes of cretinism?
A
- maternal hypothyroidism
- thyroid agenesis
- dyshormonogenetic goiter
- iodine deficiency
3
Q
what is the cause of dyshormonogenetic goiter?
A
congenital defect in thyroid hormone production - most commonly involves thyroid peroxidase
4
Q
what is myxedema? what is the result?
A
- accumulation of glycosaminoglycans in the skin and soft tissue
- deepening of voice and large tongue
