9.5 - Restrictive diseases Flashcards
1
Q
what are the findings in restrictive lung disease for:
- FEV
- FVC
- FEV : FVC
- TLC
A
- FEV: decreased
- FVC: very decreased
- FEV : FVC: increased
- TLC: decreased
2
Q
what induces the fibrosis in idiopathic pulmonary fibrosis?
A
TGFB
3
Q
what are the CT findings in idiopathic pulmonary fibrosis?
A
subpleural patches progessing to “honeycomb lung”
4
Q
which pneumoconiosis: fibrotic nodules in upper lobes
A
silicosis
5
Q
which pneumoconiosis carries an increased risk of TB? why?
A
silicosis - silica impairs phagolysosome formation by macrophages
6
Q
which pneumoconiosis: noncaseating granulomas in the lung, hilar lymph nodes, and systemic organs
A
berylliosis
7
Q
which pneumoconiosis: fibrosis of lung and pleura (plaques)
A
asbestosis
8
Q
what characteristic inclusions are seen within the giant cells of sarcoidosis granulomas?
A
asteroid bodies
