9.6 - Pulmonary hypertension

Question 1

in pulmonary HTN, the MAP is over ____ mm Hg

Answer 1

25

Question 2

what is the normal MAP?

Answer 2

10 mm Hg

Question 3

what characteristic feature is seen in pulmonary vasculature with long standing pulmonary HTN?

Answer 3

plexiform lesions

Question 4

familial forms of pulmonary HTN are due to mutations in what gene? what does the mutation do?

Answer 4

• BMPR2

- inactivating mutation leading to proliferation of vascular smooth muscle

Question 5

secondary pulmonary HTN is due to ___________ (2 causes)

Answer 5

hypoxemia or increased volume in pulmonary circuit