13.6 - Ovarian tumors

Question 1

patients with what mutation have an increased risk for serous carcinoma of the ovary and fallopian tube?

Answer 1

BRCA1

Question 2

brenner tumors are comprised of what type of epithelium?

Answer 2

bladder-like epithelium (usually benign)

Question 3

what is the serum marker used to monitor treatment of ovarian surface epithelium tumors?

Answer 3

CA-125

Question 4

cystic teratomas and embryonal carcinomas are derived from what tissue(s)?

Answer 4

fetal tissue

Question 5

dysgerminomas are derived from what tissue(s)?

Answer 5

oocytes

Question 6

endodermal sinus tumors are derived from what tissue(s)?

Answer 6

yolk sac

Question 7

choriocarcinomas are derived from what tissue(s)?

Answer 7

placental

Question 8

are teratomas benign or malignant in women?

Answer 8

benign

Question 9

struma ovarii is a _____________ (tumor type) composed primarily of _____________ tissue

Answer 9

• teratoma

- thyroid

Question 10

what is the most common malignant germ cell tumor?

Answer 10

dysgerminoma

Question 11

tumor composed of large cells with clear cytoplasm and central nuclei

Answer 11

dysgerminoma

Question 12

schiller duval bodies are seen in what type of tumor? what marker is elevated?

Answer 12

• endodermal sinus tumor

- elevated AFP

Question 13

are villi present or absent in choriocarcinomas?

Answer 13

absent

Question 14

high levels of what marker is characteristic of choriocarcinoma? what cell type produces this marker?

Answer 14

• B-hCG

- syncytiotrophoblasts

Question 15

granulosa-theca cell tumors produce ____________

Answer 15

estrogen

Question 16

histology shows reinke crystals - diagnosis?

Answer 16

sertoli-leydig cell tumor

Question 17

sertoli-leydig cell tumors (may) produce ____________

Answer 17

androgens

Question 18

fibromas are associated with what syndrome? what are the other associations?

Answer 18

Meigs syndrome

• hydrothorax
• ascites
• fibromas

Question 19

krukenberg tumors are metastatic mucinous tumors involving both ovaries that commonly originate from:

Answer 19

gastric carcinoma (diffuse type)

Question 20

what differentiates krukenberg tumors from primary mucinous carcinoma of the ovary?

Answer 20

krukenberg tumors are bilateral