16.1 - Inflammatory conditions of the breast

Question 1

what is the functional unit of the breast?

Answer 1

terminal duct lobular unit

Question 2

breast lobules and ducts are lined by what two epithelial layers?

Answer 2

• luminal cell layer (inner, milk production)

- myoepithelial layer (outer, contractile)

Question 3

during pregnancy, breast lobules undergo ____________ (hypertrophy / hyperplasia) and is driven by __________ and _____________ which are produced by the _______________

Answer 3

• hyperplasia
• estrogen and progesterone
• corpus luteum

Question 4

acute mastitis is usually due to what organism?

Answer 4

s. aureus

Question 5

erythematous breast with nipple discharge - diagnosis?

Answer 5

acute mastitis

Question 6

what drug is used to treat acute mastitis?

Answer 6

dicloxacillin

Question 7

periductal mastitis is due to inflammation of the ______________

Answer 7

subareolar ducts

Question 8

relative squamous metaplasia of lactiferous ducts (periductal mastitis) can be caused by deficiency of what vitamin?

Answer 8

vitamin A

Question 9

subareolar mass with nipple retraction - diagnosis?

Answer 9

periductal mastitis

Question 10

green-brown nipple discharge - diagnosis?

Answer 10

mammary duct ectasia

Question 11

what is seen on histology in mammary duct ectasia?

Answer 11

chronic inflammation with plasma cells

Question 12

what is seen on histology in fat necrosis of the breast?

Answer 12

calcifications and giant cells