1.2 - Cellular injury

Question 1

hypoxemia is a low __________ of oxygen in the blood

Answer 1

• partial pressure

Question 2

what is the PaO2 in anemia? SaO2? why?

Answer 2

• PaO2: normal
• SaO2: normal

all Hb bindings sites are still 100% bound by oxygen; there is just a reduction of RBCs

Question 3

what is the PaO2 in CO poisoning? SaO2? why?

Answer 3

• PaO2: normal
• SaO2: decreased

CO binds Hb more avidly than oxygen

Question 4

what is an early sign of CO poisoning?

Answer 4

headache

Question 5

what is the PaO2 in methemogloinemia? SaO2? why?

Answer 5

• PaO2: normal
• SaO2: decreased

iron in heme is oxidized to Fe3, which cannot bind oxygen

Question 6

what is the treatment for methemoglobinemia? why?

Answer 6

methylene blue - helps reduce Fe3 back to Fe2 state