13.2 - Vagina

Question 1

what is adenosis?

Answer 1

focal persistence of columnar epithelium in the upper vagina

Question 2

adenosis is a result of exposure to what chemical in utero? what is feared complication of adenosis?

Answer 2

• DES

- clear cell adenocarcinoma

Question 3

• vaginal bleeding
• grape like mass protruding from vagina or penis of a child

diagnosis? what are the micoscopic findings?

Answer 3

• embryonal rhabdomyosarcoma (sarcoma botryoides)

- rhabdomyoblasts exhibits cytoplasmic cross striations and stain positive for desmin and myogenin

Question 4

embryonal rhabdomyosarcoma (sarcoma botryoides) stains positive for what markers?

Answer 4

• desmin

- myogenin

Question 5

cancer from the lower 1/3 of the vagina goes to which lymph nodes? cancer from the upper 2/3?

Answer 5

• lower 1/3: inguinal

- upper 2/3: regional iliac