8.5 - Endocarditis Flashcards
which organism is the most common overall cause of endocarditis? what structure does it prefer to infect?
- viridans strep
- previously damaged valves
what is the most common organism responsible for IV DRUG endocarditis?
staph aureus
does staph aureus induced endocarditis lead to valvular damage?
yes (acute endocarditis)
what organism is responsible for endocarditis of prosthetic valves?
staph epidermidis
what organism is responsible for endocarditis in patients with underlying colorectal carcinoma?
strep bovis
a diagnosis of endocarditis is made, but cultures return negative. what organisms could be responsible?
HACEK:
- haemophilus
- actinobacillus
- cadiobacterium
- eikenella
- kingella
what are the clinical features of bacterial endocarditis?
- fever
- murmur
- janeway lesions
- osler nodes
- spinter hemorrhages
- roth spots
what are janeway lesions? when / where are they seen?
- erythematous nontender lesions on palms and soles
- bacterial endocarditis
what are osler nodes? when / where are they seen?
- tender lesions on fingers or toes
- bacterial endocarditis
what are splinter hemorrhages? when / where are they seen?
- hemorrhages in nail bed
- bacterial endocarditis
what are roth sports? when / where are they seen?
- embolization of septic vegetations
- bacterial endocarditis
what type of anemia is seen with bacterial endocarditis?
microcytic
what are the lab values in bacterial endocarditis for:
- Hb
- MCV
- ferritin
- TIBC
- serum iron
- % sat iron
- Hb: decreased
- MCV: decreased
- ferritin: elevated
- TIBC: decreased
- serum iron: decreased
- % sat iron: decreased
what is libman sacks endocarditis? what is a possible sequela?
- sterile vegetations that arise in association with SLE
- vegetations are present on the surface and undersurface of the mitral valve and result in mitral regurgitation