2.5 - Wound healing Flashcards
1
Q
scar formation is the result of type _____ collagen being replaced by type ____
A
- type III
- type I
2
Q
what enzyme is responsible for removing type III collagen during wound healing? what cofactor is required?
A
- collagenase
- zinc
3
Q
collagenase is responsible for removing what type of collagen during wound healing? what cofactor is required?
A
- type III
- zinc
4
Q
what is the role of TGFa during wound healing?
A
epithelial and fibroblast growth factor
5
Q
what is the role of TGFB during wound healing?
A
- fibroblast growth factor
- inhibits inflammation
6
Q
what is the role of PDGF during wound healing?
A
- growth factor for ENDOTHELIUM
- mediates skeletal development
7
Q
which mediator of wound healing is a growth factor for endothelium and mediates skeletal development?
A
PDGF
8
Q
a keloid scar is characterized by excess type ____ collagen
A
type III
