Tues Wk 3 Psych 3 Flashcards
acute lithium toxicity leads to __/__ sx
chronically, leads to gradual neuro sx like involuntary __, ataxia and T__
Lithium is filtered/reabsorbed primarily in the __ tubule
similar to sodium, thus as volume is depleted by T__ diuretic, more Li/Na is reabsorbed
this leads to __ over time
ACEI/NSAIDs also impair lithium __ and lead to toxicity
lithium conc is also inc by NDCCB like V/D
GI/neuro movements, tremor proximal Thiazide toxicity clearance
verapamil, diltiazem
drug induced parkinsonism comes from __ receptor blockers at NS pathway
usually __ gen
also antiemetics/gastric motility agent P/M
look for dec __ swing, and cogwheel __
decrease __ or use AC T/B
avoid L__ as it causes psychosis in DIP
Pt w amenorrhea and breast tenderness has drug indued __ due to risperidone
inhibits DA at __/__ receptors, also inhibiting serotonin/Alpha paths
D2 1st prochlorperazine, metoclopromide arm, rigidity dose, trihexylphenidyl, benztropine
levodopa
hyperprolactinemia
D1/D2
L__ is drug to tx gram positive VRE and MRSA
has MAOI activity, and can precipitate __ syndrome when used w SSRI
Mu opioid receptor aids in physical D__, euphoria, R/C depression, dec __ motility, sedatio, analgesia
Kappa opioid receptor leads to M, dysphoria, sedation, analgesia
Delta opioid receptor has Anti__ effects
linezolid
dependence, resp/cardio, GI
miosis
depressant
N__ is pure opioid antag used in overdose
greatest binding occurs at __ receptors
competitive w __ to displace them, reversing analgesia, sedation, RD
F__ is benzo antag to reverse intoxication effects
use psychostimulants M/A for ADHD as they have rapid onset and improvement in sx
AE include dec __ and weight loss, I__
naloxone
mu
narcotics
flumenazil
Methylphenidate, amphetamines
appetite, insomnia
tx alcohol dependence w N
antagonist of __ opioid receptor
blocks reward/reinforcing effects of __, reducing cravings
D__ inhibits acetaldehyde dehydro
causes unpleasant SE w alcohol like NV/F, D, P
A__ modulates glutamate NT at NMDA receptors
only used once abstinence is __
naltrexone
Mu
alcohol
disulfiram
flushing, diaphoresis, palps
acamprosate
achieved
use __ as antidepressant in pt w atypical __ and tx resistant depression
Atypical depression characterized by __ reactivity, __ paralysis, and rejection sensitivity
may have inc __/__
pt w combative behavior, confusion, hallucinations, w nystagmus and ataxia has __ intox
works by antagonizing __ receptors, thus releasing lots of excitatory NT
inhibits __ of NE, DA, Ser
look for __ sx like detachment and withdrawal and memory loss
MAOI, depression
mood, leaden
appetite, sleep
PCP
NMDA
reuptake
dissociative
__ lobe is responsible for executive fxn and personality
may have impaired social/emotional __ and sexual disinhibition/emotional lability
cannot perform __ tasks and purposeful actions
Left side results in A/D
Right side results in __ behavior
normal grief has feelings of sadness about __
functional decline is __
grief occurs in W__ and are specific to the deceased
always have ability for __ thngs/positive sx
frontal behavior complex apathy, depression disinhibited
deceased
less
waves
enjoying
manic episodes are more __
1 wk in __ w marked impairment requiring hospitalization
may have _ features
hypomanic is less __
observed, but slight change in __
not __ and no psych features
Bipolar 1 is presence of __ episodes
Bipolar 2 is hypomania and __ episodes
Cyclothymia is >2yrs of hypomania/depressive sx not meeting true __`
severe
length
psychotic
severe
demeanor
hospitalized
manic
depressive
dx
PCP can cause lost __ and disorientation, poor judgment, and memory loss
can also bind the __ opioid receptor
Manic episode has D, impuslivity, G, flight of ideas, inc __ and dec sleep, talkaltive
psych features usually ocur w __ sx
B__ is 5HT1A partial agonist
very slow __ as it a nonbenzo anxiolytic
no risk of T/D/W
pt w chronic anx, muscle tension, impaired conc, and fatigue has __ disorder
coordination
sigma
distrability, gradiosity, activity
manic
buspirone
onset of action
tolerance, dependence, withdrawal
generalized anx
pt w sx of mania w history of delusions/hallucinations occuring in absence of mania has __
different from BD w psychosis in that sx occur __
mood sx of mania/depression do not ever occur in S__
panic attacks must have some that are __ w no obvious trigger
strongest RF for suicide is history of ___
schizoaffective
alone
schizophrenia
spontaneous
attempted suicide
behavioral change path P\_\_ is denial of the problem C\_\_ is acceptance and thinking about change P\_\_ is planning to make change A\_\_ is putting change in place M\_\_ is maintaining change over long term
Buproprion is __ RI used for depression and smoking cessation
excessive worry, anxiety about multiple issues, difficult controlling, restless, fatigue, irritable, muscle tension, sleep probs has __ disorder
tx w CBT or __/__
second line is B/B
precontemplation contemplation planning action maintenance
ND
GAD
SSRI/SNRI
buspirone, benzo
Delirium is A__ w impaired conc
course F__ and is reversible
global memory is __
RF include D/P/prior __, inc age, sensory impairment
Brought out by drugs like N/S/A
Infections, electrolyte/__ derangements
__ illness and CNS probs
Dementia onset is G__
conc is __
progresive and I__
acute
fluctuating
impaired
dementia, parkinsons, stroke
narcotic, sedative, antihistamine
metabolic
systemic
gradual
preserved
irreversible
intense self consciousness, concerns over appearance, moodiness and need for privacy is normal __
differentiate from psychosis by looking at interactions w __
disruptive mood dysreglation is persistent irritability, freq poor tempered ___
complications of AN include O/A, cardiac __ or __ and arrhythmias
avoidant/restrictive food intake disorder has avoidance of food due to disliked __ experience
adolesence
peers
outbursts
osteoporosis, amenorrhea, atrphy, myopathy
sensory
pt w stimulant intox sx like tachycardia, HTN, hyperthermia, diaphroesis, mydriasis and psychotic sx has __ psychotic disorder
look for assc w ___
first line tx for GAD/Panic disorder is __
take a long time, w inc __/__ in this period
thus, sometimes bridge w short/intermediate acting __
Short benzos TOM
Intermediate ALT
Long CDF
substance induced
substance use
SSRI
anxiety, agitation
benzos
triazolam, oxazepam, midazolam
alprazolam, lorazepam, temazopam
Chlordiazepoxide, diazepam, flurazepam
Depersonalization/derealization disorder has __ experiences
could feel _ from self as an outside observer
or experience surroundings as __
reality testing is __
Dissociative amnesia is inability to recall important _ info usually in trauma/stress
Dissociative identity disorder is marked discontinuity in identity w formtion of __ personalities
assc w severe __/__
recurrent
detachment
unreal
intact
personal
multiple
trauma/abuse
