Friday Wk 3 Infections Flashcards
main SE of isoniazid is __
usually, mild but can lead to frank __ or severer liver dysfxn
C__ is gram pos, catalase pos, club shaped rod
grows on CT agar as black
also on Lofflers medium as stained __ w aniline dye
Bordet Gengo medium can grow __
hepatotoxicity
hepatitis
corynebacterium
Cysteine tellurite
granules
B pertussis
suspect __ poisoning w tinnitus, fever and tachypnea
in first 12h, __ alkalosis develops w inc ventilation
later, __ develops as salicylates inc lipolysis and stop OP
organic acids _ to inc AGAP
thus, after 12h should show __ ABG
bicarb and CO2 should be __ as a result
aspirin
resp
AGAP met acid
accumulate
mixed
low
Amatoxins of amanita phylloides are taken to __ via portal circ
concentrated in __ cells and bind DNA dep RNA poly __
stop __ synthesis
results in apoptosis, cell turnover and may damage _ tract
sx include ab pain, NV, severe, __ like diarrhea w blood/mucus
eventually, acute __/__ failure
urine testing for __ is dx
Ricin inhibits rRNA component of __s subunit
Euk RNA poly 1 is for __ RNA
Euk RNA poly 3 is for __ RNA
liver
hepatic, 2
mRNA
GI tract
cholera
hepatic/renal
a amantin
60
ribosomal
transfer
pt w AMS, seizure, LA, CV collapse, bright red venous blood has __ poisonin
can be due to therapy w N__ if its high dose/long duration
Nitroprusside is V__ used to control BP in HTN emergency
meabolized by R__ w sulfur molecule
forms thiocyanate, and excreted in __
w overdose, rhodense is overwhelmed, and cyanide __
tx w Sodium T__ to provide addtl sulfur
hydroxycobalamin aids in __ cyanide to excrete in urine
Sodium nitrite can induce M_ by forming cyanmethemoglobin
cyanide
nitroprusside
vasodilator
rhodanse
urine
accumulates
thiosulfate
binding
metheoglobinemia
Theophylline toxicity include NV, ab pain, diarrhea, cardaic __ and s__
major morbidity/mortality is S__
tx w Charcoal to stop GI __
BB can prevent __
bradycarida, hypoTN, hypoglycemia seen w __ overdose
tx w G__ to inc cAMP
arrhythmia, seizure
seizure
absorption
arrhythmia
BB
glucagon
most R__ have brodifacoum that acts like warfarin
causes bleeding abt __ hrs after ingestion
tx w __ and __
cryoprecipitate is factors / vWF and F
FFP is not useful for heparin overdose bc of __ enhancing heparin
rodenticides
48
FFP, VK
8, 13
AT3
Lead poisoning should be suspect in __ homes
may see neuro manifestations like regressed __, behavior probs, enceph
Gi Const, ab pain and dec __ metab
Renal w interstitial __
Hematologic w a__
screen by measuring blood __
ALA should be __ in urine
older milestones VD nephritis anemia lead inc
contact precautions for MRSA/VRE/C diff/Scabies need hand hygiene w __ as alcohol does not kill spores
Non__ gloves
G__ and private room
long duration of pain, itching, rectal bleeding indicates anal __
usually have large __ mass
assc w __ infection
HepB is a H__ virus
mature virion has hexagonal C__ covered w lipid bilayer envelope studded w proteins/carbs
partially ds __ DNA molecule
upon entry, capsid enters cytoplasm and goes to __
viral DNA then forms double stranded __ that becomes mRNA
RT has both __/__ dep DNA poly activity to create ssDNA intermediate
converts back to __ and enveloped by ER w viral proteins
soap/water
sterile
gowns
SCC
ulcerative
HPV
Hepadanaviridae capsid circular nucleus DNA
DNA/RNA
partial dsDNA
CMV/EBV are H__ family
isocahedral core w dsDNA and __ form
bud from __ membrane
HIV is a L__ retrovirus
bar shaped protein core w __ genome of 2+ ssRNA molecules
Coxsackie is P__ w isocahedral nucleocapsid and __ genome
Herpesviridae
linear
nuclear
lentivirus
diploid
picornavirus
ssRNA+
impoverished child is also at inc risk of __ poisoning
can be inhaled or __
incomplete __ allows lead to enter the CNS
lead inhibits ALAD and F__
protoporphyrin 9 cannot make heme, so __ is incorporated
inc Zn protoporphyin levels w high __
AIP does not have A__
uroporphyrinogen decarboxylase def leads to __
U__ is inc in urine
lead
ingested
BBB
ferrochelatase
Zn
ALA
anemia
PCT
uroporphyrinogen
K1 capsular polysaccharide in E coli prevents __ and complement mediated __
pathogenic for neonatal __
P fimbriae allows ascension to __
seen in __
E coli grows on EMB to ferment lactose as __ sheen
__ hemolysis on blood agar
phagocytosis
lysis
meningitis
urothelium
UTI
green
beta
