Friday Wk 3 Preg Flashcards
Gestational C__ is malignant tumor of trophoblast
usually follows __ preg
abnormal vaginal __ w very high BHCG
invades uterine wall and spreads H__ most often to lungs
look for SOB and H__
bulky, intrauterine mass that is yellow w areas of N_ and hemorrhage
abnormal proliferation of C/S without villi
invasive mole has _ hyperplastic troph w myometrial invasion
Complete mole has __ hyperplastic villi
Partial mole is __ hyperplastic
choriocarcinoma normal bleeding hematogenously hemoptysis necrosis cytotrophoblasts, synctiotrophoblasts
diffusely
diffusely
focally
baby w irritbility,, hypertonia, jittery movements, D, V, feeding intolerance, sneezing, sniffing has __ syndrome
those at risk born to mothers w poor __ health, no prenatal care, and __ infection
tx w M/M and wean the pt
Na HCO3 tx overdose of T__
Estrogen promotes __ by stimulating HMG CoA redutase
Progesterone dec __ sec to slow gastric emptying
Measles and __ both have rash starting on face that spreads to trunk
generalized LAD, esp postauricular/occipital indicates __
adults get P/P
Fetuses get D/C/P
neonatal abstinence
mental, HepC
methadone, morphine
TCA
cholesterol
bile acid
rubella
rubella
polyarthritis, polyarthralgia
deafness, chorioretinitis, PDA
mothers get insulin __ in 2nd/3rd trimesters
hPL is released by __ to inc glucose levels to supply fetus
also inc maternal L__ to release FFA/ketones to provide energy to mom
hPL stimulates panc B cell __ prodxn
if BG rises too high, __ diabetes develops
screen for GD in 3rd trimester w __ test
resistant
synctiotrophoblast
lipolysis
insulin
gestational
oral glucose tolerance
pt w vaginal bleeding and very high BHCG has __ preg
premalignant GTD w placental __ prolif
after delivery, hemostasis in placenta bed occurs due to clotting and compression via myometrial C__
MCC of postpartum hemorrhage is uterine A__
w removal of placenta in parts, think placenta A__
adheres to m__ due to scar from prior Csection
absent __ allows direct attachment, and requires hysterectomy
Placental __ is premature detachment of uterine wall
painful, prolonged C__ w tense abdomen and vag bleeding _ to delivery
molar
trophoblastic
contraction
atony
accreta
myometrium
decidua
abruption
contractions
uterine rupture presents w intense, acute __ and profuse vaginal bleeding w fetal distress
palpated as opening on __ wall
Polyhydramnios can cause uterine __ OoP to gestational age
can lead to preterm _, placental abruption, or uterine A__
also may compromise maternal __
Polyhydramnios is due to impaired swallowing via __ obstriction or anencephaly
Inc fetal urination due to __ cardiac failure (Parvo, twin-twin syndrome)
also maternal D__ and multiple gestations
any anti-__ agent inc risk of neural tube defects
pain
opening
enlargement
labor, atony
O2
GI
high output
diabetes
folate
Renal agenesis leads to O_
also seen in posterior __ valves
leads to __ sequence w flat facies, limb anomalies, pulm hypoplasia
primary oocytes are in __ of meiosis 1 until ovulation
tetrad orientation allows for DNA __
at puberty, ovulation triggers completion of __ 1 w prodxn of secondayr oocyte and polar body
secondary oocyte halts in __ 2 until fertilization
oligohydramnios
urethral
potter
prophase
recombination
telophase
metaphase
low quad screen AFP and estriol indicates __ syndrome
BHCG and inhibin should be __
Chromo21 nondisjxn occurs during O__
Omphalocele/gastroschisis/NTD/multiple gestations have inc /
Gastro has eviscerated bowel w/out __
Omphalocele has __ over multiple organs
Down
high
oogenesis
AFP/AchE
membrane
sac
Translocation down syndrome due to __ translocation bw 2 nonhomologus chromos ie 14/21
2 long arms fuse, as do 2 __
short arms have nonessential genetic material and are __
w next reproduction, fetus gets __ translocation
genotype is 46XY __
baby will be born __
because insulin cannot cross the placenta, baby must \_\_ insulin to compensate high glucose levels leads to premautre D\_\_ fetal macro\_\_ congenital malforms/RDS, \_\_ hypogly PCV and hyper\_\_
Robertsonian short arms lost unbalanced 14, 21 small
produce
delivery, somia, transient
viscosity
infant w head pointing away from soft mass in SCM muscle has congenital __
due to birth __ or malposition
may be assc w hip D__ or adducted forefoot, or __foot
may have facial __ as well
tx conservatively __
__ presents w smooth philtrum, thin vermillon border, small palpebral fissures
maternal HTN can cause __ growth restriction
torticollis trauma dysplasia, club assymetry stretching
FAS
assymetric
Prolactin is downregulated by __ in pregnancy
Estrogen/progesterone stimulate __ growth in prenatal period
after 2/3rd trimester, P is released by C__
also suppresses __/__ by AP
BHCG is produced by S__ in 1st trimester
keeps CL viable until __ can secrete hormones
levels __ later
__ is necessary for fetal renal development
thus, __/__ are teratogenic
Fetal __ is main source of amniotic fluid
low levels lead to dec diuresis and O__ w pulm hypoplasia/skull defects
may impair cranial vasc and lead to H__
progesterone
breast
corpus luteum
LH/FSH
synctiotrophoblast
placenta
fall
AT2 ACEI/ARB urine oligohydramnios hypocalvaria
M__ and L_ are first line for HTN in preg
avoid NSAID in 3rd trimester bc it dec __ closing the DA
Preeclampsia is __ HTN + proteinuria or end organ damage
Eclampsia is presence of __
Gestational HTN is just HTM w out other __
preeclampsia leads to abnormal placental V__ w hypoxia/ischemia
releases angiogenic factors w __ injury
inc permeability leads to P__
dysregulated vasc tone inc __ w end organ damage
RF include N, hx of E, O, preexisting __
methyldopa, labetolol
PGE2
gestational
seizures
manifestations
vasculature
endothelial
proteinuria
BP
nulliparity, Eclampsia, obesity, HTN
__ implants in endometrium and becomes blastocyst
blastocyst implants __ days after fert
OCM becomes C/S and releases BHCG at 8 days
Doxy localizes to E/D of developing teeth, leading to staining
do not use in kids less than _
use A__ for lyme dz instead
infant exposed to C__ can get gray skin, V, lethargy, CP collapse
S__ butyroides is rhabdomyosarcoma in young girls
jelly like __ on bladder/vaginal mucosa
morula
6
cytotrophoblast, synctiotrophoblast
enamel, dentin
8
amoxicillin
cloramphenicol
sarcoma
bunch of grapes
Complete mole has vaginal __
uterus is very very __
very high BHCG can cause HG, P, H, __ cysts
look for E__ chorionic villi w no fetal tissue
stains p57 __
microscopy shows large __ w no blood vessels, proliferated trophoblastic lining, no fetal tissue
Partial mole has vaginal bleeding and __ ab pain
uterus is __ w normal to high BHCG
p57 is __
if B HCG rises or plateaus, think __ mole
bleeding big hyperemesis gravidarum, preeclampsia, hyperthyroid, theca lutein edematous neg villi
cyclic
normal
pos
invasive
V__ interferes w folate metabolism, avoid in preg
inc risk of __
P__ use in preg has NTD, orofacial clefts, microcephaly, nail/digit hypoplasia
I__ assc w microcephaly, thymic hypoplasia, hydrocephalus
MTX has L/C abnorms, NTD and abortion
Warfarin leads to __/__ hypoplasia and stippled epiphysis
valproate
NTD
phenytoin
isotretinoin
limb, craniofacial
nasal/nail
Lithium use leads to _ anomaly
apical displacement of __ w dec RV volume and atrialization
DS assc w __ atresia, hirschprung
hypo__ and T1DM, obesity
atlantoaxial __
aromatase def is __ inherited disorder w high androgen and low estrogen
maternal __ occurs w transfer of excess androgens to mother
newborn girls have normal __ genitalia w ambiguous/male external genitalia
leads to primary __ and osteoporosis/tall
males are __ w no other abnorms
ebstein
TC valve
duodenal
thyroid
instablity
AR virilization internal amenorrhea tall
