Tues Wk 3 Psych 2 Flashcards
GABA is synthesize from __ using glutamate decarboxylase
Benzos bind to benzo binding site, __ modulating binding of GABA
this inc __ of chloride channel opening
Barbs work at __ site to prolong duration of channel opening
Baclofen works at GABA __ receptors, which utilizes a G protein
tx akathasia w dec __ dose or adding __/__
glutamate
allosterically
freq
other
B
antipsychotic, BB, benzos
R__ syndrome is neurodevelopmental disorder in girls
normal development up to __ m
loss of _/__ skills w stereotypic hand movements
decelerating __ growth w seizures, breahting abnorms
due to X linked __ geene
stimuls control therapy for insomnia dissociates bedroom from __ activities
use bed only for __, leave if not able to __
sleep hygiene maintains regular __ and avoids naps
avoid C/A/S/E before bed
Rett 18 motor/language head MECP2
stimulating
sleep, fall asleep
schedule
caffeine, alcohol, smoking, exercise
Relaxation sleep therapy promotes muscle __ in seq
use __ techniques
Sleep restriction restricts time in __ to actual sleep
Alcohol is depressant that binds __ receptors
enhances inhibitory __, which overtime leads to dec sensitivity
this excessive __ activity leads to alcohol withdrawal sx
first line therapy for alcohol withdrawal is B__ to prevent seizures/delirium
Long acting like D/C are preffered
if pt has liver disease, use LOT as they are not metabolized in liver
relaxation
breathing
bed
GABAa action stimlant benzos Diazepam, chlordiazepoxide Lorazepam, oxazepam, temazepam
most common SE in SSRI therapy is __ dysfxn
may have dec __/__ or anorgasmia/inc ejac latency
adolescents have strong need to __ w peers as they find place, separate from __ and take responsibility
better medical adherence occurs when close peers have __ cx, positive __ fxn, and immediate benefits
prefrontal cortex does not develop until __ decade
thus, teenagers cannot weigh __/__
sexual
libido/arousal
fit in
parents
similar, family
3rd
risks/benefits
postpartum __ occur w/in days, ends w/in 2 wks
sx include mild __ w tearfulness and irritability
tx w reassurance and M_
postpartum __ occurs w/in 4-6wks
sx of severe __ for > 2wks
tx w A__ and CBT
post partum psychosis onset is __
sx include D/H/bizzare behavior
tx w A/A/mood stabilizers
must have H__
blues
depression
monitoring
depression
depression
antidepressants
variable
delusions/hallucnations
AD/AP
hospitalization
__ is recurrent, anxiety provkng thought/urge/image
__ is response w repeated behaviors/actions
if time consuming, distressing, Dx is __
tx w __ and CBT
OCPD is lifelong pattern of insistence on __/__ and orderliness
Tx for narcolepsy involves promoting __
M is nonamphetamine stimulant that is first line
enhances __ signaling
separation anx disorder has physical sx like H, ab pain, N w repeated __
occurs only in __
obsessions
compulsions
OCD
SSRI
completion/perfection
wakefullness
modafinil
HA, nausea, nightmares
separation
most common cause of overdose deaths is __ abuse
2nd gen antipsychs like O/C have high risk of __ syndrome
must monitor W/W/BP/fasting __ and __ profile
Z can prolong QT
R__ is most likely to inc prolactin levels
encounters w an anxiety provoking object is __ stimulus
unlearned reaction is the unconditioned __
can pair UC stimulus w conditioned stimulus, elciting a learned, __ response
opioid Olanzapine/clozapine weight, waist, glucose, lipid ziprasidone risperadone
unconditioned
response
conditioned
pattern of angry, irritable mood, argumentative behavior, vindictive towards superiors > 6m is \_\_ dx argues/defies \_\_ deliberately \_\_ others blames \_\_ easily \_\_/\_\_
multiple motor tics (Facial __ and blinking, H/N __ w shoulder shrugging, tongue protrusion, sniffing) and vocal (Grunts, throat __ and B__, yelling) has __ dx
tx w __ or A2 __ and CBT
exacerbated by __
usually alongside A and O
Chronic tic disorder is one or more V/M tic only
ODD rules annoys others angered, annoyed
grimacing, jerking, clearing, barking
Tourette sundrome
AP, agonist
stress
ADHD/ODD
vocal/motor
lack of social engagement, speech delay, repetitive play, insisting on sameness is __ dx
problems w social R__ and nonvebal behavior
fixated __ of abnormal intensity
usually before age __
lack joint attention ie __ objects to others
motor stereotypies like hand __/spinning
indifferent to __, extreme response to __ noises
ASD reciprocity interest 2 bringing flapping pain, loud
excessive anx and preoccupation w >1 sx is __ do
intentional falsification/causing of sx w no end goal is __ do
may manipulate __ samples, alter __, induce illness
more likely in W and health care workers
like the __ role
M__ is similar, but falsifies/exaggerates sx for __ incentives
preventing suicide includes dec __, limiting access to __, managing pain, improving psychosocial __
somatic sx factitious lab, record women sick
malingering, external
stress, firearms, support
MCC of death in pt w TCA overdose is __ and refractory hypoTN
inhibit fast __ channel condx, slowing depolarization
also dec cardiac contractility and dilate peripheral venules via __ antagonists
can have __ toxicity by blocking muscarinic receptors
antidepressant, anxiolytic, seizures, tremors due to inhibiting __ NT uptake
inhibiting H1 receptor leads to S and inc appetite
cardiac arrhythmias
Na
A1
anticholinergic
presynaptic
sedation
when psychotic sx are only present during episode of major depression, diagnosis is __ w pyschosis
tx w / w ECT
schizoaffective disorder has delusions/hallucinations in __ of mood episodes
Phenelzine, Selegiline, T is __ inhibitor
normally, MAO degrades __ in presynaptic nerve terminals, allowing for inc conc
reversible, so may take __ of discontinuation for MAO to return
major risk of __ w MAOI and SSRI
normally, MAO receptors __ w inhibition due to high conc
MD
AD/AP
absence
trancyclopromine, MAO
monoamines
2w
Serotonin syndrome
downregulte
C__ is 2nd gen antipsychotic best for schizophrenia/ esp w suicidiality
SE are A/S/M and met syndrome
THC stimulates cannabinoid __ and __ receptors
look for __ injection, tachycardia, inc __ and dry mouth
use caution w Trazadone and other cx predisposing to priapism like S and M
Trazadone antagonizes postsynaptic serotonin __ and inhibits serotonin __
alpha blocker that can lead to __ hypoTN and priapism
antag of H1 receptor leading to S__
clozapine
agranulocytosis, seizure, myocarditis
CB1/CB2
conjunctival, apetite
sickle cell, MM
receptors, reuptake
orthostatic
sedation
children delelop understanding of gender by age __, becomes permanent by __
developmentally normal to __ opposite gender activities
gender dysphoria is prolonged/intense feeling that gender does not match assigned __
inc rate of __ illness, depression, anx
NT __ is primary cause of OCD
4, 6
explore
sex
psych
__ is acute onset confused state
disoriented, A__ and psychosis w __ disturbances
secondary to underlying __ cx, so tx primary cause
also tx w high potency first gen AP like H in low doses
Low potency FGA cause non neuro SE like S__ due to H1 blockade
__ SE due to cholingeric blockage
ortho hypotn due to __ blockade
examples include C/T
High potency FGA cause __ sx
H/F are examples
delirium
agitated, sleep
medical
Haloperidol
sedation
anticholinergic
A1
chlorpromazine, thioridazine
extrapyramidal se
haloperidol/fluphenazine
