Thurs Wk 3 Infectious Dz 4 Flashcards
pt w __ deficits get recurrent Neisseria infections
forms pore leading to __ disturbances, inflow of water and cell __
N men presents w fever, chills, __ skin rash small vessel vasculitis on palms, soles
leads to __ shock w out tx
pts who produce too much __ can also have recurrent neisseria infections
IgA blocks __/__ from activating complement, thus no bacteriocidal effect
Fusion inhib E binds to HR1 of gp41 to stop cell fusion
MAC electrolyte lysis petechial septic
IgA
IgM/IgG
Enfuviritide
NNRTI are __ RT inhibs
NRTI are __ RT inhibs
Maraviroc allosterically blocks gp120 from interacting w ___
S__ is nonlactose fermenting, oxidase neg, motile gram neg
has Vi antigen as __ to prevent opsonization
sickling of __ vasculature leads to necrosis w potential for mucosal __
this seeds bone and leads to __
Staph aureus osteomyelitis is caused by adhesion to __
allosteric
competitive
CCR5
salmonella capsule intestines breakdown necrosis
collagen
Acyclovir is excreted into urine via glomerular __ and tubular secretion
when conc exceeds solubility, crystallization/crystalluria and __ occur
prevent by __ dose and ensuring adequate hydration
Protein A is virulence factor of outer __ layer in Staph aureus
binds to __ portion of IgG preventing complement activation
Parvo presents w acute symmetric transient __ of joints in adults
can interrupt __ w profound anemia and CHF in fetuses
leads to pleural/pericardial __ and ascites
known as fetal __
filtration
damage
dec
peptidoglycan
Fc
arthralgias
erythropoeisis
effusion
hydrops
TORCH
Toxo is caused by obligate intracellular __
see C, IC __ and hydroceph
ZVZ presents w limb __ and cutaneous scarring, C and chorioretinitis
Syphillis presents w H__ and skeletal abnorms
Rubella is enveloped __ virus
__ deafness, cataracts, __ rash, PDA and HSM
CMV causes D_ and __ calcifications w jaundice, chorioretinitis
HSV can cause cutaneous __/__ and scarring
protozoa
chorioretinitis, calcifications
hypoplasia, cataracts
HSM
ssRNA
sensorineural, blueberry muffin
Deafness, paraventriclar
vesicles, lesions
polyprotein precursors are encoded by G/P/E genes
only __ is glycoslyated to gp160
this is cleaved to gp120 and __
gp120 mediates viral attachment by binding __ of susceptible cells
gp41 anchors __ through interacts aiding fusion
RT is incorporated into __ virion and cleaved into viral enzymes during maturation
Chancroid has gram stain described as __ chain
MRSA is freq carried in __
gag, pol, env env gp41 CD4 gp120
mature
school of fish
anterior nares
N men is commonly transmitted via __
thus, close contacts need __
can use R__ which enters all body comparments
or C/C
Penicillin/cephalosporin bind __ to PBP such as transpeptidase
growth of vegetative organisms results in characteristic \_\_ wound w central necrosis and black eschar in B anthracis spreads via \_\_ to blood and multiplies C\_\_ is most common form transmitted via \_\_ or bioterrorism Pulm form is will \_\_ the pt
respiratory droplets
rifampin
Cipro/Cextriaxone
irreversibly
edematous lymphatics cutaneous animals kill
in prokaryotes, 30s ribosomal subunit scans for __ sequence and recognizes AUG n formylmethionine tRNA
energy provided by __ to bring 50S in
drugs that bind to 30s cause genetic code __
initial n-formylmethionine binds at __ site of ribosome
Always use AG alongside bacterial __ inhibitor to allow for entry
Vancomycin can also cause O__
inhibit peptidoglycan __
Shine delgarno
GTP
misreading
P
cell wall
ototoxicity
synthesis
both Mycoplasma/Chlamidophila pna have __ bilayer membrane
dx gonorrhea w __ test
uses male __ or female urine, V__ or endocervical secretion
untx gonorrhea can progress to P/E
__ may have forchhemier spots on soft palate
phospholipid
NAAT
urine
vaginal
prostatitis, epidydimitis
rubella
Roseola infantum caused by __
children < __ yo
3-5 days of high fever w __ maculopapular rash
starts on __ and spreads to face/extremities
HHV6
2
blanching
trunk
