Thurs Wk 3 Infectious Disease 2 Flashcards
red blood cells in malaria have small rings called T__
tx begins w C___, add M__ if resistance is possible
also can use A/P and artemisinins
P vivax/ovale have __ forms thus require P__
Ivermectin used for O__
Mebendazole for A/T/hookworn/pinworm
N__ for chagas
Mucor can survive in __ due to ketone reductase enzyme allowing for survival in acid/hyperglycemia
may release __ from binding proteins during KA
acquired via __
trophozoites
chloroquine, mefloquine
atovaquon/proguanil
primaquine
onchocerciasis
ascaris, trichuris
nitrofuritox
DKA
heme
inhalation
think __ w chorioretinitis and clustered pustule skin lesions in neutropenic pt
Erythema infectiousum presents w systemic sx and rash that spares __ folds
reticular rash then is found on / due to immune complex deposition
replicates in __ precursors in BM by attaching to __
viral replication then leads to cell _
major polysaccharide component of fungal cell wall is __
blocked by E__ antifungals
thus stopping cell wall __
usually for C/A
Terbinafine inhibits __ epoxidase to dec ergosterol synthesis
candida
nasiolabal
trunk/extremities
RBC, P antigen
lysis
b glucan
echinocandin
synthesis
candida/aspergillus
squalene
nontreponemal tests VDRL/RPR test for anti-__-cholesterol-lecithin antigen
clumping indicates __ as lipids are released from cells damaged by Treponema
non__
Treponemal tests directly test __ antigens
Amphotercin b causes __ leading to renal toxicity
may have toxin to renal __ cells, leading to ATN and RTA
if pt responds well, may switch to P__
cardiolipin
positivity
specific
treponemal
vasoconstriction
posaconazole
Echinococcus granulosus is most common cause of H__ cysts
found in Eastern world and __ US in sheep/dog exposure
initial infection is __ but subsequent exposure may lead to __ involvement
unilocular lesion indicates __ and multilocular indicates E _
larvae implant in __ and trigger release of Mono/Eosin
cyst is __ (eggshell) w fluid and budding cells
outer wall forms __ sheet w thick capsule
can tx w A__ or surgery, w risk of spillage and __ shock
baby w trismus, problems feeding, hypertonicity, clenched hands, opisthotnos, RD has neonatal __
assc w unhygenic __ or cord separation
tx w vaccinating __, which provides transplacental __
hydatid SW asx liver E granulosus multilocularis capillaries calcified gelatinous albendazole, anaphylactic
tetanus
delivery
mother
IgG
in pt w HIV, lung/GI tumor can be __
look for red flat maculopapular or raised __ nodules/masses
__ cells w atypia and BV proliferation
may have extravasated __
CMV presents w multiple __ and erosions
look for cytomegalic cells and __ bodies
Crypto has non __ inflam
basophilic __ seen
Entamoeba forms discrete, __ shaped ulcers
biopsy shows __ containing RBC
Kaposi sarcoma
hemorrhagic
spindle
RBC
ulcers
inclusion
ulcerative
clumping
flask
trophozoites
malaria w fever sweating every 48 hours are __ and include P __/__ and falciparum
all organisms transmitted by __ mosquito and go to liver
infect hepatocytes and __ w release of merozoites
these infect __ and result in lysis
Vivax/ovale form __ in latent hepatic infection
must use __ to eradicate hypnozoites
Enterobiasis adults live in __ in cecum/appendix
females migrate to __ skin and deposit eggs
released and can __ host or spread
eggs/worms in perianal area produces __ w pain, NV
dx w __ tape test for oval, __ eggs
A__ is tx
P__ pamoate is 2nd line/regnant
tertian vivax/ovale Anopheles replicate RBC hypnozoites primaquine
intestines perianal reinfect itching scotch flat albendazole pyrantel
Diethylcarbamezepine for L and lymphatic __
Paragonimiasis/Clonorchis/Paragnimiasis gets P__
Ziduvidine binds to RT and is incorporated into viral genome as __ analog
has azido group at 3’ and not __, thus stopping chain elongation
Acyclovir is monophosphorylated by viral __ in RLS
then __ enzymes for active triphos form
EBV/CMV fo not have same __ thus are relatively uninhibited by acyclovir
loa loa, filiariasis
praziquantel
thymidine
hydroxyl
TK
cellular
TK
pt w synehaam chorea has nonrhytmic __ of hand/feet/face w sudden changes in __
seen in __ as antibodies are directed against M protein and N-acetyl-beta-D__
this attacks __ in heart and lysoganglioside in __
Recomb takes place in __ viruses
Reassortment is seen in __ viruses
Elderly pt w fever, hypoTN, AMS and e coli likely has ___ due to UTI
E coli, Enterobacter, Klebsiella are most common __ orgs
E coli has adhesive __ allowing for urethral contamination and ascension
movements
voice
ARF, glucosamine
myosin, CNS
nonsegmented
segmented
septic shock
UTI
fimbriae
Gram neg sepsis occurs due to LPS __
severe sepsis has __ dysfxn from poor blood flow
can lead to __ w poor tissue perfusion
white plaques on tongue that can be scraped off to showing erythematous mucosal surface has __
KOH shows __ and hyphae
oral thrush indicates __
Cutaneous candida due to __ and __ in groin/perianal area
Leukoplakia is __ scratched off
endotoxin
organ
LA
candida
yeast
immunosuppression
heat, humidity
not easily
__ is rubeola virus
enveloped, nonsegmented __ sense RNA
transmitted via __
look for __ spots an maculopapular exanthem on trunk/extremities
may progress to __ and secondary bacterial infects
can lead to __ comps over time
prevent w __ vaccine
P__ is used for malaria/toxo as it inhibits parasitic DHFR
Imipenem binds __ protein to stop peptidoglycan synth
use w __ to stop renal metabolism by inhibiting dehydropeptidase
Sulfa drugs inhibit _ synthetase
measles negative inhalation Koplik PNA neuro live
pyramethine
penicillin binding
cilastatin
dihydropterate
triad of polyarthralgia, dermatitis, and tenosynovitis indicates __ infection
pt w blistering eruption w formation of golden yellow crust has __ impetigo
can be __ or __
__ is MC comp of Strep pyo
can occur after pharyngeal/_infections
ARF is less common, only occuring after __ infection
tx impetigo w topical ab M_
AMS, HA, focal neuro defects w CSF showing hemorrhagic lympho pleocytosis has __ enceph
usually in bilateral __ lobes
tx w IV __
Disseminated gonococcal
nonbullous staph, GAS PSGN skin pharygeal
mupirocin
HSV
temporal
acyclovir
RNase H removes RNA primer in __
can be targeted alongside __ in therapy
pt w blanching, erythematous rash and petechial erruption has __
Erythema multiforme is __ disorder following HSV
numerous __ lesions at distal extremities
L__ occurs after spirochete Leptospria
acquired via __ urine
erythema of Lyme disease spreads outward as bacteria__
HIV
RT
RMSF
hypersensitivity
leptospirosus
animl
migrate
__ is nonmotile, encapsulated gram pos rod found in clumps of chinese letters
cytoplasm has __ that stain w aniline dye
B toxin allows __ to EGFR receptor on cardiac/neural cells
A subunit then stops __ synth
colonizes __ and acts locally to promote necrosis w __ exudate
look for sore throat, fever, cervical LAN, coalescing__
comps include __ failure, and cardiac/neural __
C diptheria granules bindng protein respiratory tract fibrinous pseudomembrane resp, toxicity
Strep
Alpha hemolytic
Strep pneumo is optochin __ and bile __
Viridians is optochin __ and bile __
Beta hemolytic
Pyogenes is PYR __ and Bactitracin __
GBS is PYR __ and CAMP __
Gamma hemolytic Enterocci grows in \_\_ and \_\_ saline PYR is \_\_ Gallolyctis assc w \_\_ grows in \_\_ only, PYR is \_\_
senstiive, soluble
resistant, insoluble
pos, sensitive
neg, pos
bile, hypertonic pos colon cancer bile neg
pt w wool exposure, especially goat, could have __
inhaled into __ and ingested by macros
spead to mediastinal LN and cause __ mediastinitis
spores germinate and produce __ w myalgia, fever, malaise, wide mediastinum, bloody pleural __ and death
has antiphagocytic __ containing capsule
nonhemolyzing __ colonies that look serpentine like M__
acute measles depletes __ resulting in keratitis and corneal ulcers
supplement to reduce __
B anthracis alveoli hemorrhagic toxin effusion d glutamate adherent medusa
VA
morbidity
