Immunity: Flashcards
What are phagocytes, b cells and t cells?
= different types of white blood cells
= b and t cells are lymphocytes
What are antigens?
= protein (polysacharide) that triggers your body to generates antibodies
= produces an immune response by stimulating specific t and b cells
What are antibodies?
= proteins that are specific to a particular antigen + complementary
What is a non-specific immune response?
= response that is the same for every pathogen (antigen)
What is a specific immune response?
= response that is specific to that particular antigen on the pathogen
= involves stimulation for t + b cells + secretion of anti-bodiesn
What is a primary response?
= multi-step pathway from the anti-gen presenting cell to the secretion of of antibodies
What is secondary response?
= stimulation of the memory b cells to cause massive secretion of antibodies quickly after an infection
= quicker than primary
What is a cell meditated response?
= by t cells
= they only bind to antigens on a host cell
= (antigen presenting cell)
=
What is a humoural response?
= by b cells + antibody secretion
= antibodies are soluable and can enter tissue fluid
+ destorys pathogens
What is agglunation?
= when antibodies bind to antigens the bacteria cells become clumped together, and acts as markers to stimulate phagocytosis
What is antigen varability?
= pathogen has a high rate of mutation
= genes of pathogen changes, leading to different antigens on cell surface membrane
= antibodies have no effect
Barriers to pathogen entry (3)
= HCL in stomach
= mucus in epithelial = skin
Difference between B-cells and T-cells (2)
= b-cells mature in bone marrow
= t-cells mature in thymus gland