Cell Structure: Endoplasmatic Reticulum and Golgi Apparatus. Flashcards
Once a protein has been formed what happens?
= folds into it’s 3d shape
= can be modified further
= e.g: carbonhydrates molecules attached to form glycoproteins
Why are genetic modification of protiens important?
= for it’s function.
What are the different destinations of protein?
= function in cytoplasm
= sent to organelles
= inserted into cell membranes
= secreted from the cell
Ribosomes consist of how many sub units?
= 2
= each sub unit contains a different number of protiens + ribosomal RNA
Where are ribosomes found?
= most in cytoplasm and rough ER.
What is the structure of the rough ER?
= sheets of membranes
= forms flattened sacs- cisternae
= membranes covered in ribosomes
What does the ribosomes on the rough ER do?
= translation takes place for protiens which are:
= secreted from the cell
= protiens for cell membrane + lysosomes
How does the ribosome on the rough er carry out translation? 1
= a molecule of mRNA attaches itself and translation takes place
= growing polypeptide chain passes through the membrane and into the lumen of the rough ER
=
How does the ribosome on the rough er carry out translation? 2
= in the lumen the polypeptide chain folds into a teritery structure
= goes through the rough ER
= during this the polypeptide can be modified
How does the ribosome on the rough er carry out translation? 3
= polypeptide is packed into vesicles
= transported to golgi aparatus
= when makes it way through it can me modifided further
What is the structure of the golgi aparatus?
= consist of sheets of flattened sacs called cisternae
=can be modified further when making its way through
= reach it’s final structure- functional protien
Once the protien has complected it’s journey through the golgi aparatus what happens?
= packaged into vesicles
= can fuse with the cell membrane and protien can be secreted from the clel
What can happen alternativley to the protien?
= protien can form part of the cell membrane
or
= protien can enter vesciles to form lysosomes
What does the final destination of any protien depend on?
= amino acid sequence
= or how the protien was modified
= how it was modified
What are some key points?
= cells that secrete a lot of protien will have a lot of rough eR
= some endoplasmatic reticulum are not covered in ribosomes (smooth)
=