Enzymes: Competitive inhibitor

Question 1

What are competitive inhibitors?

Answer 1

= similar structure to substrate- can bind to the active site
= NO reaction happens
= after short time it leaves the active site

Question 2

What happens when it occupies the active site for a period of time?

Answer 2

= prevents actual substrate from binding
= frequence of collisions between substrate and active site are reduced
= reduces rate of reaction
=

Question 3

How can we reduce the effect of a competitive inhbitor?

Answer 3

= increasing substrate concentration

Question 4

What does an increased substrate look like on a graph?

Answer 4

= rate increases as substrate concentration increases
= certain point: does not increase any further, all active sites are occupied so rate is at maxiumn
= maximum vmax

Question 5

What are irreversible competitive inhibitors?

Answer 5

= bind permantely to the active site
= cannot reverse the effect by increasing substrate concentration