Biological Molecules: Protien Structure 1

Question 1

What is a primary structure of a protein?

Answer 1

= specific order of amino acids in a polypeptide
= important as it helps determine the 3d shape of the protien - shape is critical for function

Question 2

What happens if you change a single amino acid in a primary structure?

Answer 2

= can change the final shape of a protien
= prevent a protien from carrying out it’s function properly

Question 3

What is the primary structure of a polypeptide determined by?

Answer 3

= DNA sequence of the gene that encodes that polypeptide

Question 4

All along the polypeptide chain what can be seen?

Answer 4

= C=O groups
= N-H groups
= Oxygen atoms in the C=O group have a small negative charge
= Hydrogen atoms in the N-H group has a small positive charge
= attracts eachother and hydrogen bonds form between amino acids along the chain

Question 5

What is a secondary structure?

Answer 5

= The hydrogen bonds cause the polypeptide chain to twist and fold into shapes

Question 6

When the polypeptide chain twists and coils what does this form?

Answer 6

= alpha helix
= COMMON
= helical shape held in place by hydrogen bonds
=

Question 7

When the polypeptide chain folds what does this form?

Answer 7

= beta pleated sheet
= hydrogen bonds between the aminon acids hold into place

Question 8

What can many proteins have in their structure?

Answer 8

= regions with alpha helices
= regions with beta pleated sheets
= type of secondary structure formed depends on primary structure in that region