DNA replication: Flashcards

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1
Q

Every time a cell underogoes cell division what happens?

A

= All the dna is copied
= DNA replication

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2
Q

What happens in the first stage?

A

= enzyme DNA helicase attaches to the DNA molecule
= causes hydrogen bonds between the complementary base pairs to break
= causes 2 polynucleotide strands to seperate from eachother

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3
Q

What happens secondly?

A

= free nucleotides line up with their complementary bases on the DNa strands
= held into place by hydrogen bonds between the complementary bases
= not bonded by phosphodiester bonds

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4
Q

What are these free nucleotides called and what are they?

A

= activated nucleotides
= contains 3 phosphate heads
=

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5
Q

What happens thirdly?

A

= a 2nd ezyme attaches
= DNA polymerase
= moves down the molecule and catalyses the formation of a phosphodiester bond between the activated nucleotides
= this causes the activated nuclotides to loose their 2 other phosphate heads- as they leave it provides energy for the reaction

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6
Q

What are we now left with?

A

= two copies of double stranded dna molecule
= each contains one strand from the original DNA molecule+ brand new
= semi-conservative replication

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7
Q

What is a mutation?

A

= when an incorrect base is inserted into the growing polynucleotide strand causes the DNA sequence to change
= effects the organisms
= random and occur spontanously
=

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8
Q
A
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