Why Subtle Gene Changes Mean Every Child is Different - Symposia Part 2 Flashcards
1
Q
ICS =
A
Inhaled Corticosteroid
2
Q
LABA =
A
Long-acting beta 2 agonist
3
Q
LTRA =
A
Leukotriene receptor antagonist
4
Q
Asthma - Suspected v Diagnosed
A
5
Q
LABA, ICS, LTRA Comparisons
A
6
Q
Case Study - Asthma - Jamie, 7yo
- Recurrent Wheeze, 2 hospital admissions and 2 further A&E visits over 12 months, managed with inhaled salbutamol plus intravenous prednisolone
- Low lung function with 15% response to bronchodilator
- On Seretide 125 inhaler plus aerochamber 1 puff twice daily plus regular oral motelukast
- Still uses the blue inhaler several times daily
- Proper inhaler technique, he is taking it well
- Very organised family, you don’t think there is a problem with not taking medicines regularly
A
7
Q
Case Study - Asthma - Jamie, 6 YO
- Active and well until 6 months ago
- now coughs a lot when chasing football, falls behind his friends during play, coughs at night
*
A
8
Q
Case Study - Asthma, Ben 10YO
- Hay fever symptoms, exposed to cigarette smoke, wheezes when he plays with cats
- Asthma control is poor
- On inhaled beclomethasone 200 micrograms 2x daily
- How would we manage this child?
A
9
Q
… Exposure reduces trigger load and can reduce hospital admissions (Asthma)
A
HDM
10
Q
Summary - Individualising asthma management
A
11
Q
Triggers have a cumulative effect - leading to underlying … (Asthma/allergies)
A
inflammation