Sexually Transmitted Diseases Flashcards

1
Q

Who gets STIs?

  • … having sex… BUT the risk groups are:
    • Young age (
    • Frequent partner change, high no. lifetime partners, C… (simultaneous partners)
    • … orientation
    • E… for some STIs
    • Residence in …/d…
    • Use of non … …
    • History of …
A
  • ANYONE having sex… BUT the risk groups are:
    • Young age (<20 years) - lower age at 1st intercourse, ‘coitarche’
    • Frequent partner change, high no. lifetime partners, concurrency (simultaneous partners)
    • Sexual orientation
    • Ethnicity for some STIs
    • Residence in inner city/ deprivation
    • Use of non barrier contraception
    • History of previous STI
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2
Q

Coitarche means …

A

The first sexual intercourse

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3
Q

Does age at first intercourse (coitarche) affect rate of STI?

A

Yes - lower age = more likely

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4
Q

Is early age intercourse associated with poor subsequent sexual health?

A

Yes

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5
Q

Young people and STIs

  • Behaviourally more vulnerable to STI acquisition
    • Why? (5)
A
  • Behaviourally more vulnerable to STI acquisition
    • higher numbers of sexual partners / partners change
    • greater numbers of concurrent partners
    • yet to develop skills and confidence to use condoms, negotiate safe sex
    • more risk-taking behaviour/ experimentation
    • poor awareness contraception
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6
Q

What does this image show?

A

A normal cervix

  • Cervical ectropion – transformation zone – changing from columnar epithelium to squamous epithelium
  • Chlamydia and gonorrhoea infect columnar epithelium
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7
Q

Chlamydia and gonorrhoea infect where? (Cervix)

A

Chlamydia and gonorrhoea infect columnar epithelium

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8
Q

Percentage of all STIs occuring in young adults (16-24)

  • 16-24 year olds only make up …% of population
  • BUT - STI proportion in this age is much … (e.g. chlamydia …-…% is among this age)
A
  • 16-24 year olds only make up 12% of population
  • BUT - STI proportion in this age is much higher (e.g. chlamydia 55-75% is among this age)
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9
Q

Rates of chlamydia diagnoses by gender and age - England,2019

A
  • Males tend to go for younger females so disproportion with gender
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10
Q

Rates of chlamydia diagnoses by gender and age - England,2019

A
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11
Q

The earlier intercourse occurs, the higher the proportion:

  • Express … they had not …
  • Report being … or … willing than their partner
    • …% men and …% women express … they had not …
A
  • Express regret they had not waited longer
  • Report being more or less willing than their partner
    • 20% men and 42% women express regret they had not waited longer
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12
Q

Early intercourse - associated with vulnerabilities:

  • leaving home / not living with parents before … years
  • leaving … early
  • family … & …
  • lack of … relationships
  • those whose main source of information on sex was not .. or ..
A
  • leaving home / not living with parents before 16 years
  • leaving school early
  • family disruption & disadvantage
  • lack of nurturing relationships
  • those whose main source of information on sex was not school or parents
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13
Q

Where do young people get information? (regarding sex)

  • Parents? School? Books? Internet??
  • …% daily searches access porn sites
  • Most common Google search term: “…”
  • Unintended exposure reported by …% of 15-17yo while searching or checking e-mails
  • Intended viewing - …% teenagers view porn regularly; 1:… every day
A
  • Parents? School? Books? Internet??
  • 25% daily searches access porn sites
  • Most common Google search term: “sex
  • Unintended exposure reported by 70% of 15-17yo while searching or checking e-mails
  • Intended viewing - 58% teenagers view porn regularly; 1:10 every day
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14
Q

% teenagers view porn regularly; 1: every day

A

58% teenagers view porn regularly; 1:10 every day

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15
Q

Negative aspects? - associated with porn

  • Unrealistic … & …
  • …-image / performance …
  • Lack of … / boundaries – hardcore material becomes … / normalised
  • Ethical issues: … of women, … blurred
  • Lack of … use: reduced risk perception, need to practice safe sex
A
  • Unrealistic nature & expectations
  • Self-image / performance anxiety
  • Lack of censorship / boundaries – hardcore material becomes addictive / normalised
  • Ethical issues: exploitation of women, consent blurred
  • Lack of condom use: reduced risk perception, need to practice safe sex
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16
Q

Main messages to get across to young people - Sex

A
  • Don’t rush into it – avoid peer pressure
  • Use condoms with all new partners
  • Get a STI screen when you have a new partner
  • Sort out contraception
  • Avoid overlapping sexual relationships
  • GBM* should also get vaccinated for hepatitis A/B and HPV & consider HIV PrEP (Gay and Bisexual Men)
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17
Q

Gay, bisexual and other men who have sex with men (MSM) are … likely to be diagnosed with bacterial STIs than other men

A
  • Gay, bisexual and other men who have sex with men (MSM) are more likely to be diagnosed with bacterial STIs than other men
  • Over the last decade, there has been a steady increase in the number of new STI diagnoses among MSM. Gonorrhoea has increased from 4,938 diagnoses in 2010 to 33,853 in 2019.
  • MSM account for most syphilis and gonorrhoea diagnoses in men.
  • Numbers of HIV diagnoses have been decreasing since 2015 largely due to the scale up of a combination of HIV prevention methods
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18
Q

Rates of gonorrhoea diagnoses by Gender and Age - England 2019

A
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19
Q

Rates of STI diagnoses by ethnic group amongst males: England, 2019

A
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20
Q

Rates of STI diagnoses by ethnic group amongst females: England, 2019

A
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21
Q
  • The rate of gonorrhoea in BME people is …x that of the general population
  • For trichomoniasis, the rate in BME people is …x that of the general population
A
  • The rate of gonorrhoea in BME people is 4x that of the general population
  • For trichomoniasis, the rate in BME people is 9x that of the general population
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22
Q

Sexual networks & core groups

  • Definition of a “core group”
    • ..-… of the population – high …
A
  • Definition of a “core group”
    • sub-group of the population – high turnover
    • not a static entity
    • highly sexually active individuals
    • high prevalence of infection
    • reservoirs of infection
    • high frequency of transmission
  • Effective control at the population level based on targeting core groups
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23
Q

Effective control at the population level based on targeting … … (Sexually Transmitted Infections/Diseases)

A

Effective control at the population level based on targeting core groups (Sexually Transmitted Infections/Diseases)

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24
Q

Rates of STI diagnoses by index of multiple deprivation quintile: England, 2019

  • Rates of STI diagnoses were highest among those living in the .. … areas of England.
A

Rates of STI diagnoses were highest among those living in the most deprived areas of England.

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25
Q

GMC guidance - Genital Examination

  • Offer a …
  • Explain to patient why examination is … & what it will …
  • Give patient …
  • Obtain patient’s … before the examination
  • … if patient asks you to
  • Keep discussion … - avoid unnecessary comments
A
  • Offer a chaperone
  • Explain to patient why examination is necessary & what it will involve
  • Give patient privacy to undress & dress
  • Obtain patient’s permission before the examination
  • Discontinue if patient asks you to
  • Keep discussion relevant - avoid unnecessary comments
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26
Q

Female genital examination

  • Inspect … area, … & … area
  • Look between … …
  • Inspect & … … region
  • Leg … - allow better …
  • … examination (use water as lubricant-gels can interfere with tests)
  • … examination (if indicated)
A
  • Inspect pubic area, vulva & perianal area
  • Look between skin folds
  • Inspect & palpate inguinal region
  • Leg rests - allow better visualisation
  • Speculum examination (use water as lubricant-gels can interfere with tests)
  • Bimanual examination (if indicated)
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27
Q

Female genital examination – can you name A-M?

A
  • A - mons pubis
  • B - clitoral hood and anterior fourchette
  • C - clitoris
  • D - vestibule
  • E - anus
  • F - labia majora
  • G - labia minora
  • H - urethra
  • I - hymen / hymenal remnants
  • J - introitus
  • K - bartholins glands
  • L – posterior fourchette
  • M – perineum
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28
Q

Male genital examination – can you name the anatomy

A
  • S – shaft
  • F – foreskin
  • COS – coronal sulcus
  • G – glans
  • M – meatus
  • Fr – frenulum
  • GC – glans corona - corona of glans (we don’t use this term much – GC in sexual health usually means gonococcus or gonorrhoea!)
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29
Q

Male genital examination

  • Inspect … area, … region
  • Inspect … & … area
  • … scrotal contents – note presence of testes, any lumps/ tenderness
  • Inspect penis - record whether … - if not inspect under …
  • Particular attention to coronal …, F… & M..
  • Note presence of urethral …
A
  • Inspect pubic area, inguinal region
  • Inspect scrotum & perianal area
  • Palpate scrotal contents – note presence of testes, any lumps/ tenderness
  • Inspect penis - record whether circumcised - if not inspect under foreskin
  • Particular attention to coronal sulcus, frenulum & meatus
  • Note presence of urethral discharge
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30
Q

What are Pearly penile papules?

A
  • Pearly penile papules are small dome-shaped to thread-like skin-coloured bumps that are typically located on the sulcus or corona of the glans penis.
  • normal - sometimes more prominent in some than others - no removal
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31
Q

Genital appearances - Enlarged sebaceous glands and Epidermoid cysts are often mistaken for … by patient

A

Genital appearances - Enlarged sebaceous glands and Epidermoid cysts are often mistaken for infection by patient - they are considered cosmetic (NHS)

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32
Q

Malignant melanoma can be found on the …

A

genitals

33
Q

Psoriasis can also be found on the …

A

genital area

34
Q

Tinea cruris – a dermatophyte (…) infection - can be found on the …

A
35
Q

pruritic papules on genitals - check the … - what might it be?

A

check hands - might be scabies

36
Q

Bacterial/protozoal vs. viral STIs

A
37
Q

Bacterial / protozoal * STI’s include … (4)

A

Chlamydia, gonorrhoea, syphilis, TV* (trichomonas vaginalis)

38
Q

Chlamydia, gonorrhoea, syphilis, TV* are all what kind of STI? (viral or bacterial/protozoal?)

A

Bacterial/protozoal STI

39
Q

Viral STI’s include … (4)

A

Herpes, warts, HIV, hepatitis

40
Q

Herpes, warts, HIV, hepatitis are all what kind of STI? (Viral or Bacterial/Protozoal?)

A

Viral STI’s

41
Q

Features of Viral STI’s, such as Herpes, Warts, HIV and hepatitis

  • many … of infection
  • … presentation
  • diagnostic tests may be …
  • … treatment only
  • often …-…
  • … reservoirs
A
  • many unaware of infection
  • delayed presentation
  • diagnostic tests may be unreliable
  • symptomatic treatment only
  • often life-long
  • expanding reservoirs
42
Q

Features of Bacterial/Protozoal STI’s, such as Chlamydia, gonorrhoea, syphilis, TV (Trichromonas vaginalis):

  • more often … symptoms
  • … presentation
  • … diagnosis
  • … treatment available
  • c…
  • reservoirs can be …
A
  • more often florid symptoms
  • early presentation
  • rapid diagnosis
  • effective treatment available
  • curative
  • reservoirs can be controlled
43
Q

Which out of bacterial/protozoal or viral STI’s can be treated?

A

Bacterial/protozoal - viral is symptomatic treatment only

44
Q

People with … STI’s may be unaware of infection

A

Viral (Herpes, warts, HIV, hepatitis)

45
Q

Gonorrhoea: microscopic

  • typical gram-… intracellular diplo…
  • microscopic examination of a smear of … exudate (men) of … secretions (women)
A
  • typical gram-negative intracellular diplococci
  • microscopic examination of a smear of urethral exudate (men) of endocervical secretions (women)
46
Q

Primary syphilis

  • how long after contact?
  • red mark -> raised spot -> … at the site of contact
  • Enlarged … … in the groin/neck
  • Heals within …-… weeks
A
  • weeks after contact (9-90 days)
  • red mark -> raised spot -> ulcer at the site of contact
  • Enlarged lymph nodes in the groin/neck
  • Heals within 1-3 weeks (with or without treatment)
47
Q

Secondary syphilis

  • ..-.. weeks after primary stage - lasts for ..-.. weeks
  • Systemic dissemination - millions spirochaetes
  • …-like illness, headache, lymphadenopathy
  • … ulcers - “snail track” painless
  • Condylomata lata - white/grey lumps in moist areas
  • A…
  • … resolution with effective treatment
  • Particularly suspect if rash involves … & …
A
  • 2-6 weeks after 10 stage - lasts for 2-4 weeks
  • Systemic dissemination - millions spirochaetes
  • Flu-like illness, headache, lymphadenopathy
  • Mouth ulcers - “snail track” painless
  • Condylomata lata - white/grey lumps in moist areas
  • Arthritis
  • Rapid resolution with effective treatment
  • Particularly suspect if rash involves palms & soles
48
Q

Secondary syphilis occurs how many weeks after primary stage?

A

2-6 weeks

49
Q

Secondary syphilis lasts for how long?

A

2-4 weeks

50
Q

If infection (Rash) involves palms and soles, what STIs are suspected? (what is the differential diagnoses?)

A

HIV and Secondary Syphilis (main) also non STI - pityriasis rosea (no herald patch)

51
Q

Secondary syphilis involves the … and …

A

palms and soles

52
Q

Trichomonas vaginalis

  • … cell protozoan parasite
  • Infects … & …
  • d.., d…
  • Causes … discharge, “… cervix”
  • Diagnosed by seeing … organisms on microscopy
  • Responds well to …
A
  • Single cell protozoan parasite
  • Infects vagina & urethra
  • Dysuria, discharge
  • Causes frothy discharge, “strawberry cervix”
  • Diagnosed by seeing motile organisms on microscopy
  • Responds well to metronidazole
53
Q

Trichomonas vaginalis responds well to …

A

Responds well to metronidazole

54
Q

Trichomonas vaginalis causes what kind of discharge?

A

Causes frothy discharge, “strawberry cervix”

55
Q

Viral STI’s are …

A

HIV, hepatitis, HPV, herpes

56
Q

Genital warts

  • How common?
  • What virus?
  • Type … and Type … in 90%
  • What types are related to cervical cancer?
A
  • Extremely common
  • Human papilloma virus (HPV)
  • Type 6 & 11 in 90%
  • Vs types 16 & 18, 31, 33 etc. (cervical cancer)
57
Q

HPV types 16 & 18, 31, 33 etc can cause what type of cancer?

A

Cervical cancer

58
Q

What HPV types can cause cervical cancer?

A

16, 18, 31, 33

59
Q

What are the most common HPV types? (90% of cases)

A

6 and 11

60
Q

Number of anogenital warts (first episode) diagnoses by sexual risk: England, 2015 to 2019

A
61
Q

Introduction of vaccine for HPV (Australian data)

A
62
Q

Molluscum contagiosum

  • What are they?
A
  • Molluscum contagiosum is an infection caused by a poxvirus (molluscum contagiosum virus). The result of the infection is usually a benign, mild skin disease characterized by lesions (growths) that may appear anywhere on the body.
  • common in kids - not STI related
63
Q

Herpes simplex type 1 & 2

  • Symptoms
    • painful …, …, vaginal …
    • … symptoms e.g. fever and myalgia (more common in first occurrence)
    • recurrences generally … severe
  • Signs
    • blistering & … (+/- cervix/rectum)
    • painful inguinal lymphadenopathy
    • heals after …-… days
A
  • Symptoms
    • painful ulceration, dysuria, vaginal discharge
    • systemic symptoms e.g. fever and myalgia (more common in first occurrence)
    • recurrences generally less severe
  • Signs
    • blistering & ulceration (+/- cervix/rectum)
    • painful inguinal lymphadenopathy
    • heals after 5-14 days
64
Q

What are the symptoms of Herpes Simplex T1 and T2?

A

Painful ulceration, dysuria, vaginal discharge - possibly systemic symptoms also (fever, myalgia - more common in first occurence)

65
Q

Herpes Simplex T1 and T2 heals after … - … days

A

5-14 days

66
Q

Only 1:… people aware they have herpes (…%)

A

Only 1:5 people aware they have herpes (20%)

67
Q
  • Oral HSV: usually type …
  • Genital HSV: …% type 1, …% type 2
A
  • Oral HSV: usually type 1
  • Genital HSV: 50% type 1, 50% type 2
68
Q

Non-Sexually Transmitted Infections

  • What 2 infections are there?
A
  • Candida / thrush
  • Bacterial vaginosis
69
Q

Candida / thrush

  • f… infection
  • not an …
  • symptoms (3)
  • … rash in males
  • treatment is … …
A
  • fungal
  • not an STI
  • itching, discharge, swelling
  • papular rash in males
  • treatment is topical antifungals
70
Q

Bacterial vaginosis

  • symptoms - discharge / “…” odour
  • imbalance of vaginal …
  • overgrowth of …
  • often result of … / …etc.
  • responds to …
A
  • discharge / “fishy” odour
  • imbalance of vaginal flora
  • overgrowth of anaerobes
  • often result of over-washing / bubble baths etc.
  • responds to metronidazole
71
Q

Complications of STIs

A
72
Q

Complications of Chlamydia / gonorrhoea

A
  • PID, epididymitis, infertility, chronic pain, seronegative arthritis +/- urethritis and conjunctivitis
73
Q

Complications of HPV / warts

A
  • cervical cancer, anal/vulval/penile intraepithelial neoplasia (AIN/VIN/PIN)
74
Q

Complications of Bacterial vaginosis and Trichomonas vaginalis

A
  • miscarriage, early labour, low-birth weight (pregnant)
75
Q

Complications of Syphilis

A
  • dementia, cardiac abnormalities etc etc - tertiary stage progression
76
Q

Complications of Hepatitis B, hepatitis C

A
  • cirrhosis, liver cancer
77
Q

Complications of HIV

A
  • opportunistic infections, lymphoma, non-AIDS malignancies
78
Q

Most STIs increase the risk of … transmission

A

Most STIs increase the risk of HIV transmission

79
Q

Summary of STI’s

A
  • Rates of STIs are increasing because of changing behaviour, communication, globalisation
  • Certain groups are more vulnerable to STIs due to links with core groups through sexual networks
  • Patients may present with ‘normal anatomy’ or non-STI pathology
  • Differences between bacterial vs viral infections
  • Serious complications therefore correct diagnosis & prompt treatment essential