Topography of the Brain Flashcards
… - development of the brain
Neurulation - development of the brain
Neurulation - development of the brain
- Embryonic day …
- Neuroectoderm cells receive inductive signals from …
- Cells thicken to form neural … - early NS
- Lateral neural plate margins fold inwards to form neural …
- Embryonic day 20
- Neuroectoderm cells receive inductive signals from notochord
- Cells thicken to form neural plate - early NS
- Lateral neural plate margins fold inwards to form neural tube

Neurulation - development of the brain
- Embryonic day 20
- Neuroectoderm cells receive inductive signals from notochord
- Cells thicken to form neural … - early NS
- Lateral neural plate margins fold inwards to form neural tube
- Embryonic day 20
- Neuroectoderm cells receive inductive signals from notochord
- Cells thicken to form neural plate - early NS
- Lateral neural plate margins fold inwards to form neural tube

… forms primitive nervous system
Ectoderm forms primitive nervous system
Running along the whole length of mesoderm is a rod like structure known as the noto…
Running along the whole length of mesoderm is a rod like structure known as the notochord

The Neural tube forms around day …
Neural tube - day 20

Neural tube - has neural crest cells
- These differentiate into 4 different types:
- Autonomic and sensory neurons and glia
- Cells of the … gland
- Epidermis
- …/connective tissue of the head
Neural tube - has neural crest cells
- These differentiate into 4 different types:
- Autonomic and sensory neurons and glia
- Cells of the adrenal gland
- Epidermis
- Skeletal/connective tissue of the head

Neural crest cells migrate into periphery and differentiate into 4 types and neural tube thickens - All around embryonic day …
Neural crest cells migrate into periphery and differentiate into 4 types and neural tube thickens - All around embryonic day 24

Neurulation
- The nervous system develops when the notochord induces its overlying ectoderm to become neuroectoderm and to develop into the neural …. The neural … folds along its central axis to form a neural groove lined on each side by a neural fold. The two neural folds fuse together and pinch off to become the neural …
- The nervous system develops when the notochord induces its overlying ectoderm to become neuroectoderm and to develop into the neural plate. The neural plate folds along its central axis to form a neural groove lined on each side by a neural fold. The two neural folds fuse together and pinch off to become the neural tube.

The bulk of our neural tube is called the …layer
The bulk of our neural tube is called the mantle layer - this becomes the brain parenchyma

The mantle layer of the neural tube becomes the brain …
parenchyma
Ependymal layer of the neural tube lines the …
ventricles of adult nervous system

The lumen of the neural tube becomes the … and … canal of our spinal cord
The lumen of the neural tube becomes the ventricles and central canal of our spinal cord

What day of neuralation does the neural tube thicken?
neural tube thickens - All around embryonic day 24
Neural tube defects occur in about 1 in every … established pregnancies
Neural tube defects occur in about 1 in every 1000 established pregnancies
Failure of the anterior neuropore to close means … will develop
anencephaly (Fatal) - less common

Failure of the posterior neuropore to close means … will develop
Failure of the posterior neuropore to close means Spina bifida will develop (divided by a cleft)

Anencephaly - … herniates out of foetus - degeneration of … - fatal
Anencephaly - Forebrain herniates out of foetus - degeneration of forebrain - fatal
Spina Bifida - … aspect fails to close - divided by a cleft - open vertebral canal
Spina Bifida - posterior aspect fails to close - divided by a cleft - open vertebral canal
2 types of SB : … (hidden, vertebral arch defect only) or … (e.g. meningocele = meninges projects out)
2 types of SB : occulta (hidden, vertebral arch defect only) or cystica (e.g. meningocele = meninges projects out)

Risk of neural tube defects is decreased by taking what during pregnancy?
folic acid
Primary Brain Vesicles
- P…
- M…
- R…
- Prosencephalon
- Mesencephalon
- Rhombencephalon

- Prosencephalon form the …
- Mesencephalon form the …
- Rhombencephalon form the …
- Prosencephalon form the forebrain
- Mesencephalon form the midbrain
- Rhombencephalon form the hindbrain
Development of the flexures (brain)
- 2 flexures:
- … flexure (near mesencephalon)
- … flexure (between rhombencephalon and spinal cord)
- 2 flexures:
- Cephalic flexure (near mesencephalon)
- Cervical flexure (between rhombencephalon and spinal cord)

















































































