Pancreas - Part 3 Flashcards
What remains increased longer than serum amylase in episodes of acute pancreatitis?
Urine amylase
What is the normal range for serum lipase?
10-140U/L
What does serum lipase increase with? (6)
- Pancreatitis
- Obstruction of the pancreatic duct
- Pancreatic carcinoma
- Acute cholecystitis
- Cirrhosis
- Severe renal disease
What is the normal range of glucose in a fasting patient?
< 100mg/dL
What is the normal range of glucose in a patient 2 hours postprandial?
< 145 mg/dL
What does glucose increase with? (3)
- Severe diabetes mellitus
- Chronic liver disease
- Overactivity of several of the endocrine glands
What does glucose decrease with?
Tumours of the islets of Langerhans in the pancreas
What are causes of acute pancreatitis? (5)
- Biliary disease
- Alcohol abuse
- Trauma
- Peptic ulcer disease
- Idiopathic
What are the clinical findings of acute pancreatitis? (4)
- Abrupt onset of epigastric pain
- Nausea/vomiting
- Elevated lipase and amylase
- Paralytic ileus
What is the US appearance of acute pancreatitis? (4)
- Normal findings
- 30% - Decrease in parenchymal
echogenicity - Smooth borders
- Enlargement
What are 2 differential diagnosis for acute pancreatitis?
- Normal pancreas
2. Neoplasm
Chronic pancreatitis
Repeated, prolonged, or persistent attacks of pancreatitis
What are the causes of chronic pancreatitis? (2)
- Hypocalcemia
2. Hyperlipidemia
What are the clinical findings of chronic pancreatitis? (5)
- Chronic RUQ or epigastric pain
- Nausea/vomiting
- Weight loss
- Abnormal glucose tolerance test
- Normal amylase and lipase values
What is the US appearance of chronic pancreatitis? (6)
- Increase in parenchymal echogenicity
- Irregular borders
- Calcifications
- Pseudocyst formation
- Atrophy
- Prominent pancreatic duct