Biliary System - Part 6 Flashcards
What is the 5th most common malignancy?
GB carcinoma
What are the risk factors for GB carcinoma? (5)
- Cholelithiasis
- Porcelain GB
- Cholecystitis
- Female prevalence
- Greater than 60 years of age
What are the clinical findings for GB carcinoma? (8)
- Asymptomatic
- RUQ pain
- Palpable mass
- Jaundice
- Anorexia
- Nausea/vomiting
- Elevated alkaline
phosphatase - Mild increase in AST and ALT levels
What is the US appearance for GB carcinoma? (6)
- Thick, irregular GB wall
- Irregular intraluminal mass
- Immobile mass
- Cholelithiasis
- 90% of cases - Lymphadenopathy
- Metastatic liver lesions
What are 5 differential diagnosis for GB carcinoma?
- Adenoma
- Sludge
- Cholecystitis
- Adenomyomatosis
- Metastases
Is GB carcinoma more common in male or females?
Females
What are the direct extensions of metastatic GB disease? (3)
- Pancreas
- Stomach
- Bile duct
What are the indirect extensions of metastatic GB disease? (4)
- Melanoma
- most common - Lung
- Kidney
- Esophagus
What are the clinical findings for metastatic GB disease? (5)
- Asymptomatic
- RUQ pain
- Jaundice
- Nausea/vomiting
- Elevated alkaline
phosphatase
What is the US appearance for metastatic GB disease? (3)
- Focal GB wall thickening
- Irregular intraluminal mass
- Non-shadowing
- Absence of gallstones
What are 3 differetial diagnosis for metastatic GB disease?
- Cholecystitis
- Adenoma
- Primary carcinoma
What are the complications of acute cholecystitis? (5)
- Ascending cholangitis
- Empyema
- Perforation
- Pericholecystic
or liver abscess - Septicemia
What are the causes of acute cholecystitis? (3)
- Obstruction of the cystic duct
- Infection
- Idiopathic
What are the risk factors of acute cholecystitis? (3)
- Female prevalence
- Cholelithiasis
- 40-50 years of age
Is acute cholecystitis more common in male or females?
Females