Liver - Part 7 Flashcards
What is another term for hepatocellular carcinoma?
Hepatoma
What is the cause of a hepatoma? (3)
- Cirrhosis
- Chronic hepatitis B
- Exposure to carcinogens in food or environment
What are the clinical findings for a hepatocellular carcinoma? (7)
- Palpable mass
- Abdominal pain
- Weight loss
- Unexplained fever
- Elevated ALT, AST, and alkaline phosphatase
- Positive AFP
- Jaundice
What is the US appearance for a hepatoma? (5)
- Solid mass with variable echogenicity
- May demonstrate a hypo echoic halo
- Multiple nodules or diffuse infiltrative masses may also be demonstrated
- Hepatomegaly
- Ascites
What are 5 differential diagnosis for hepatocellular carcinoma?
- Metastases
- Abscess
- Cavernous
hemangioma - Adenoma
- Cirrhosis
Where does the majority of metastases occur?
Colon
- then pancreas, breast and lung
What are the clinical findings for metastases? (7)
- Hepatomegaly
- RUQ pain
- Weight loss
- Loss of appetite
- Jaundice
- Increase in AST, ALT, and bilirubin
- Mild increase in alkaline phosphatase
What is the US appearance for metastases? (5)
- Bull’s-eye or target lesion
- Hyper echoic masses
- Cystic masses
- Complex masses
- Diffuse pattern
What are 4 differential diagnosis for metastases?
- Multiple abscesses
- Nodular cirrhosis
- Fatty infiltration
- Multiple cavernous
hemangiomas
What are causes of Budd-Chiari syndrome? (3)
- Hepatoma
- Tumor extension (renal or liver)
- Hematologic disorder
What are the clinical findings for Budd-Chiari syndrome? (4)
- Abdominal pain
- Hepatomegaly
- Lower-extremity edema
- Mild increase in alkaline phosphatase
What is the US appearance of Budd-Chiari syndrome? (9)
- Hypo echoic intraluminal echoes in the hepatic veins (thrombus)
- Dilated hepatic veins
- Vein wall thickening
- Absence of or altered hepatic venous flow
- Hepatomegaly
- Enlarged caudate lobe
- Ascites
- Hyper echoic liver parenchyma
- Thrombosis in the portal veins
What are 3 differential diagnosis for Budd-Chiari syndrome?
- Cirrhosis
- Portal vein
thrombosis - Technical error
What are the causes of portal hypertension? (5)
- Cirrhosis
- Hepatitis
- Fatty infiltration
- Portal vein obstruction
- Budd-Chiari syndrome
What are the clinical findings of portal hypertension? (6)
- Splenomegaly
- Hepatomegaly
- Increase in LFTs
- Hematemesis
- Jaundice
- Abdominal distention