Study aid (138 - 176) Flashcards
- What is the causative agent of syphilis?
Treponema pallidum subspecies pallidum
- How can syphilis spread?
By sexual contact, transplacental, by blood transfusion and by organ transplantation.
- What is the first symptom in syphilis?
Ulcus durum – painless hard ulcer, enlarged lymph nodes.
- In which stage of the syphilis can appear rush all over the body?
2nd stage.
- In which stages is syphilis contagious?
1st and 2nd stages and in the first 2 years of the latency. At 3rd stage only in utero infections may occure.
- When can develop neurosyphilis during the infection?
In all stages of the diseases can develop neuroyphilis.
- What is the specific diagnosis of the syphilis?
ELISA, TPHA, TPPA
(Treponema pallidum particle agglutination (TP-PA) i)
- When can be used non treponemal serological reactions during the infection?
- RPR and VDRL is used to determine the stages of syphilis
- To detect the reinfection
- To control the effectiveness of the therapy
(RPR (rapid plasma reagin) is a screening test for syphilis)
- What are the non-specific treponemal serological reactions?
RPR and VDRL
- What kind of diseases can be caused by Borrelia?
Lyme diseases and relapsing fever
- How can the Lyme disease spread?
By the bite of tick.
- What are the causative agents of Lyme disease? (3 examples)
Borrelia burgdorferi, Borrelia afzelli, Borrelia garini
- What is the causative of epidemic relapsing fever?
Borellia recurrentis. (recurrent fever)
- What is the vector of Lyme diseases?
Tick
- What is the vector of Borrelia recurrentis?
Body louse
- What is the molecular background of relapsing fever?
Bacterial antigen changing.
- What is the first symptom of Lyme diseases?
Erythema chronicum migrans
(bull’s eyes rash)
- What is the causative agent of Weil’s diseases?
Leptospira icterohaemorrhagiae.
- What are the characteristic properties of the meningitis caused by Leptospira?
Serosus, non-purulent.
- What is the source of the infection caused by Leptospira?
Zoonotic diseases, can spread by the urine of animals.
- How can the Lyme diseases diagnosed?
By serology, ELISA screening test and fro confirmation immunoblot is used.
- Which bacteria cannot have cell wall?
Mycoplasma, Ureaplasma.
- Which bacteria can cause atypical pneumoniae?
Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila.
- What is the causative agent of typhus exanthematicus?
Rickettsia prowaczekii
- What is the causative agent of Q-fever?
Coxiella burnettii
- What is the causative agent of parrot fever?
Chlamydophila psittaci.
- What is the causative agent of trachoma?
Chlamydia trachomatis, serotype A-C.
- What kind of disease can be caused by Chlamydia trachomatis serotype L1-L3?
Lymphogranuloma venereum.
- What is the effect of the bacterial AB exotoxins?
They are: neurotoxins, protein synthesis inhibitors or ion secretion enhancers.
- What is the effect of the cholera toxin?
Increasing of the cAMP, enhancing the ion secretion
- What are the causative agents of impetigo contagiosa?
S.aureus, S.pyogenes
- What is the causative agent of erysipelas?
Streptococcus pyogenes
- What is the causative agent of Trachoma?
Chlamydia trachomatis A,B,C
- What is the causative agent of Ophtalmoblenorrhoea neonatorum?
Neisseria gonorrhoeae
- List 4 capsulated bacteria from the list below!
- Streptococcus pneumoniae
- Streptococcus agalactiae
- Streptococcus pyogenes
- Escherichia coli
- Haemophilus influenzae
- Neisseria meningitidis
- Listeria monocytogenes
- How many percentage of the adults are carrier of Staphylococcus. aureus?
20-30%
- How many different kind (serotype) of capsule can be produced by Streptococcus pneumoniae?
94 (accepted answer: 90-100)
- What is the most common causative agent of community acquired pneumonia?
a. Streptococcus pneumoniae
- What kind of vaccines can be used to prevent invasive diseases caused by Streptococcus pneumoniae
a. Prevenar-13: Streptococcus pneumoniae 13 type of capsule conjugated to toxoid – recommended for new-borns and in elderly
b. Pneumovax: Streptococcus pneumoniae 23 type of capsule – recommended for adults and teenagers.