III - A. Virology | 15. Paramyxoviruses (RSV, Paramyxoviruses) Flashcards

1
Q

I. Basics
1. What are the viruses belong to PARAMYXOVIRUSES group?

A

Name: „Para”= next to; „myxo”= mucus – mucosal infections

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2
Q

I. Basics
2. What are the genetic material and morphology of

A
  • Non-segmented (-)ssRNA genome
  • Enveloped
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3
Q

II. Parainfluenza virus
1. How does Parainfluenza virus spread?

A

Spread: respiratory droplets
- Common infections, esp. in children

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4
Q

II. Parainfluenza virus
2a. What are the diseases caused by Parainfluenza virus?

A
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5
Q

II. Parainfluenza virus
2B. What are the features of Croup?

A
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6
Q

II. Parainfluenza virus
3. What is the diagnosis of Parainfluenza virus?

A

Clinical signs, X-ray: steeple sign

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7
Q

II. Parainfluenza virus
4. What is the treatment of Parainfluenza virus?

A

Tx: no treatment against the virus
(cold humid air / steroid inhalation or suppository (Rectodelt)
/ bronchodilatator inhalation (Ventolin) / oxigen therapy / intubation )

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8
Q

II. Parainfluenza virus
5. Do we have vaccine for Parainfluenza virus?

A

Vaccine not available, under trial

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9
Q

III. Respiratory syncytial virus - RSV
1. How does Respiratory syncytial virus - RSV spread?

A
  • Spread: respiratory droplets
  • Common infection, nosocomial spread also possible
  • Usually spread in autumn, winter, among children and elderly
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10
Q

III. Respiratory syncytial virus - RSV
2. What are the clinical forms of Respiratory syncytial virus - RSV?

A
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11
Q

III. Respiratory syncytial virus - RSV
3. How do we diagnose RSV?

A
  • Clinical
  • RSV PCR or antigen testing from nasal sample if necessary
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12
Q

III. Respiratory syncytial virus - RSV
4. What is the treatment for RSV?

A

No treatment available against the virus (Bronchodilators, epinephrine, and corticosteroids)

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13
Q

III. Respiratory syncytial virus - RSV
5. What is the Prevention for RSV?

A

Palivizumab – monoclonal antibody for premature babies (mRNA vaccine in trial)

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