III - A. Virology | 7. DNA and RNA tumor viruses Flashcards

1
Q

I. Basics
1. Explain mode of action of oncogenic viruses in general

A
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2
Q

I. Basics
2. Give a summary of types of tumor viruses

A
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3
Q

I. Basics
3. What are the DNA tumor viruses?

A
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4
Q

I. Basics
4. What are the RNA tumor viruses?

A
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5
Q

II. DNA tumor viruses
1A. What are the herpesviruses that can cause tumors?

A
  1. EBV: Burkitt lymphoma, oral hairy leukoplakia, nasopahryngeal carcinoma
  2. HHV8: Kaposi sarcoma
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6
Q

II. DNA tumor viruses - Herpesviruses
1B. What are EBV associated tumors?

A
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7
Q

II. DNA tumor viruses - Herpesviruses
1C1. What are the features of HHV8 - Kaposi Sarcoma Virus?

A
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8
Q

II. DNA tumor viruses - Herpesviruses
1C2. What are the detection and treatment for HHV8 - Kaposi Sarcoma Virus?

A
  1. Lab Detection: viral DNA or antigen from tumor tissue or lymphocytes
  2. Treatment: surgical, liquid nitrogen, radiation
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9
Q

II. DNA tumor viruses
2A. What are the features of HPV?

A

Human Papillomavirus - HPV: oral and genital papilloma, carcinoma
- low and high-risk types

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10
Q

II. DNA tumor viruses
2B. What are the low-risk types of HPV?

A
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11
Q

II. DNA tumor viruses
2C. What are the high-risk types of HPV?

A
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12
Q

II. DNA tumor viruses - Human papilloma virus (HPV)
2D. What is the diagnosis for Human papilloma virus (HPV)?

A

Diagnosis: PCR
(Genital cancer screening: PAP smear: to detect potentially precancerous
and cancerous processes in the cervix)

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13
Q

II. DNA tumor viruses - Human papilloma virus (HPV)
2E. What are the treatment and prevention for Human papilloma virus (HPV)?

A
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14
Q

II. DNA tumor viruses - Poxviridae: molluscum contagiosum virus
3A. What are the transmission and treatment of MOLLUSCUM CONTAGIOSUM VIRUS?

A
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15
Q

II. DNA tumor viruses - Poxviridae: molluscum contagiosum virus
3B. What is the treatment of MOLLUSCUM CONTAGIOSUM VIRUS?

A

cryotherapy, curettage: removal, Potassium hydroxide

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16
Q

II. DNA tumor viruses - Hepatitis B virus
4A. What are the features of Hepatitis B virus in causing cancer?

A
17
Q

II. DNA tumor viruses - Hepatitis B virus
4B. How do we diagnose Hepatitis B virus?

A

PCR, serology from blood

18
Q

III. RNA turmor viruses
1. What are the RNA viruses that can lead to cancer?

A
  • Hepatitis C virus: hepatocellular carcinoma
  • HTLV: leukemia (ATLL)
19
Q

III. RNA turmor viruses
2. What are the features of Hepatitis C virus?

A
20
Q

III. RNA turmor viruses
3. How do we diagnose Hepatitis C virus?

A

PCR, serology from blood