IIA. Systemic Bacteriology | 8. Klebsiella, Enterobacter, Serratia. Flashcards
I. Klebsiella genus
1. What are the general features of Klebsiella genus?
- Gram negative rod
- Ubiquitous
- Normal intestinal flora (Enterobacteriaceae)
- Polysaccharide capsule
- Non-motile
- Lactose fermenter
- Facultative anaerobe
I. Klebsiella genus
2. Give examples of Klebsiella genus
K. pneumoniae
K. oxytoca
K. granulomatis
K. rhinoscleromatis
K. ozaenae
I. Klebsiella genus
3. What are biochemical properties of Klebsiella genus?
I. Klebsiella genus
4. Describe Pathogenesis & clinical features of Klebsiella genus
- Facultative pathogens
- Lobar pneumonia (Friedländer pneumonia) → K. pneumoniae
- Urinary tract infections
- Sinusitis, Otitis media, Cholecystitis, Cholangitis
- Wound infections, Sepsis
I. Klebsiella genus
5A. What is the diagnosis for Klebsiella genus?
I. Klebsiella genus
5B. How should we use culture for the diagnosis of Klebsiella genus?
- Simple agar: mucoid colonies with urine smell
- EMB agar: purple colonies
I. Klebsiella genus
5C. How should we use Biochemical tests for the diagnosis of Klebsiella genus?
glucose, lactose, urease + / indole, –
I. Klebsiella genus
5D. How should we use serology for the diagnosis of Klebsiella genus?
capsule swelling test
I. Klebsiella genus
6. What is the treatment for Klebsiella genus?
- Multidrug resistant
- ESBL
- MBL
- Antibiotic susceptibility test
- Carbapenems, Monobactams, Fluoroquinolones, Aminoglycosides
I. Klebsiella genus
7. what are the features of Klebsiella pneumonia?
- Member of the normal intestinal flora
- Diseases:
● lobar pneumonia
● UTI, sinusitis, otitis
● Wound infection
I. Klebsiella genus
8. What is the feature of Klebsiella oxytoca?
iatrogenic
(relating to illness caused by medical examination or treatment.)
I. Klebsiella genus
8. What is the feature of Klebsiella oxytoca?
iatrogenic
(relating to illness caused by medical examination or treatment.)
I. Klebsiella genus
9. What is the feature of Klebsiella ozaenae?
Infection of mucous membrane in nasal cavity cavity
II. Enterobacteriaceae Family
1. What are the main features of Enterobacteriaceae Family?
● Naturally appearance: soil, water, vegetation and animals GI
● Morphology: 2-4 m rod
● Gram-negative
● Oxidase -negative
Either normal flora or cause pathogenesis
MOTILE
II. Enterobacteriaceae Family
2. What are the Two main types of infectious disease are associated with Enterobacteriaceae?
● intestinal diseases
● extraintestinal diseases