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AA Microbio Semifinal > III - A. Virology | 13. Picorna and Caliciviruses > Flashcards

III - A. Virology | 13. Picorna and Caliciviruses Flashcards

1
Q

I. Picornaviruses
1. What are the features of Picornaviruses? (include genetic material and morphology)

A
  • Name: Pico-RNA: „small RNA viruses”
  • Non-enveloped viruses: resistance to environmental conditions
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2
Q

I

A
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3
Q

I. Picornaviruses
2. How do Picornaviruses spread?

A

from the environment, mostly feco-orally

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4
Q

I. Picornaviruses
3A. What are the most important picornaviruses?

A
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5
Q

I. Picornaviruses
3B. What are the most important Picornaviruses of enterovirus genus?

A
  • Poliovirus
  • Coxsackie A & B viruses
  • Rhinoviruses
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6
Q

I. Picornaviruses
3C. What are the most important Picornaviruses of hepatovirus genus?

A
  • Hepatitis A virus
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7
Q

I. Picornaviruses - poliovirus
4A. What are the features of poliovirus?

A
  • Belongs to Enterovirus genus
  • Does not cause enteric disease!!
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8
Q

I. Picornaviruses - poliovirus
4B. How does poliovirus spread?

A
  • Sheds and spread from the enteric system with stool – fecooral infection
  • Resistant to environmental factors and acids
  • Poor hygiene/sanitation enhances the spread
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9
Q

I. Picornaviruses - poliovirus
4C. What are the symptoms of poliovirus?

A
  • Most of the infections are asymptomatic
  • Can lead to severe central nervous system infection with paralysis and death
  • Eradicated from most of world via vaccination
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10
Q

I. Picornaviruses - poliovirus
4D. What is the Clinical presentation of poliovirus?

A
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11
Q

I. Picornaviruses - poliovirus
4E1. What are the diseases caused by poliovirus?

A

POLIOMYELITIS – PARALYTIC POLIO

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12
Q

I. Picornaviruses - poliovirus
4E2. What are the features of poliomyelitis - paralytic polio?

A
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13
Q

I. Picornaviruses - poliovirus
4E3. what is Post-polio syndrome?

A

progressive muscle weakness in polio survivors decades later

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14
Q

I. Picornaviruses - poliovirus
4F. How do we prevent disease caused by poliovirus (poliomyelitis)?

A
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15
Q

I. Picornaviruses - poliovirus
4G. What is the diagnosis for disease caused by poliovirus (poliomyelitis)?

A

PCR from CSF

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16
Q

I. Picornaviruses - poliovirus
4i. What is the treatment for disease caused by poliovirus (poliomyelitis)?

A
  • No antiviral therapy
  • Ventilation, physiotherapy, surgery for contractures
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17
Q

I. Picornaviruses - rhinovirus
5A. What are the features of rhinovirus?

A
  • Name: „Rhinos”: nose in Greek
  • More than 100 serotypes – we can get infected that many times
  • Very frequent infections
18
Q

I. Picornaviruses - rhinovirus
5B. How does rhinovirus spread?

A

Spread: respiratory droplets, contaminated hands

19
Q

I. Picornaviruses - rhinovirus
5C1. What is the clinical representation of rhinovirus?

A

Clinical representation: RHINITIS / COMMON COLD
- Nasal discharge, nasal obstruction, sneezing, coughing
- Self-limiting infection, last ~ 1 week
- Tx: no specific treatment; analgesics, decongestants

20
Q

I. Picornaviruses - rhinovirus
5C2. What is the treatment for rhinovirus?

A

no specific treatment; analgesics, decongestants

21
Q

I. Picornaviruses - Coxsackie A and B viruses
6A. What are the features of Coxsackie A and B viruses?

A

Worldwide distribution, mostly affecting children

22
Q

I. Picornaviruses - Coxsackie A and B viruses
6B. How does Coxsackie A and B viruses spread?

A

respiratory droplets and feco-oral route

23
Q

I. Picornaviruses - Coxsackie A
6C1. What are the 3 diseases caused by Coxsackie A?

A
  • HERPANGINA
  • CONJUNCTIVITIS
  • HAND, FOOT, AND MOUTH DISEASE
24
Q

I. Picornaviruses - Coxsackie A
6C2. What are the symptoms and treatment for HERPANGINA caused by Coxsackie A?

A
  • Mostly affects children
  • Sy: High fever, sore throat, herpes-like oral vesicules
  • Tx: self-limiting, analgestics
25
Q

I. Picornaviruses - Coxsackie A
6C3. What is CONJUNCTIVITIS?

A

Acute hemorrhagic eye infection, pain, swollen eyelids

26
Q

I. Picornaviruses - Coxsackie A
6C4. What are the symptoms and treatment for HAND, FOOT, AND MOUTH DISEASE caused by Coxsackie A?

A
27
Q

I. Picornaviruses - Coxsackie B
7A. What are the 2 diseases caused by Coxsackie B?

A
  1. Pleurodynia
  2. Myocarditis
28
Q

I. Picornaviruses - Coxsackie B
7B. What are the features, symptoms and treatment for

A
28
Q

I. Picornaviruses - Coxsackie B
7B. What are the features, symptoms and treatment for Pleurodynia caused by Coxsackie B?

A
29
Q

I. Picornaviruses - Coxsackie B
7C. What are the features, symptoms and treatment for myocarditis caused by Coxsackie B?

A
30
Q

I. Picornaviruses
8. Make a summary of diseases caused by COXSACKIE A AND B VIRUSES?

A
31
Q

II. caliciviruses
1. What are the genetic material and morphology of caliciviruses?

A

RNA viruses, no envelope - resistant

32
Q

II. caliciviruses
2. How does caliciviruses spread?

A
33
Q

II. caliciviruses
3. What is the clinical presentation of caliciviruses?

A
34
Q

II. caliciviruses
4. What is the diagnosis for caliciviruses?

A
  • based on symptoms
  • rarely PCR from stool
35
Q

II. caliciviruses
5. What is the treatment for caliciviruses?

A

replacement of lost fluids
=> IV infusion if needed

36
Q

III. Extra
1. Make a summary of enteric viruses

A

Picornaviruses and caliciviruses

37
Q

III. Extra
2. What is Diagnostics of viral infections?

A

PCR and/or serology

38
Q

III. Extra
3. What is Treatment of viral infections?

A

Usually nothing available
- Except eg. HIV, hepatitis B, C, herpesvirus, influenza

39
Q

III. Extra
4. What is prevention of viral infections?

A

Vaccination !

AA Microbio Semifinal (99 decks)

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