Endocrino: Conceitos básicos Tireoide Flashcards

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1
Q

Qual a função da tireoperoxidase?

A

Juntar iodo com a tireoglobulina

MIT + DIT = T3

DIT + DIT = T4

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2
Q

Principal transportador de T3 e T4 na circulação:

A

TBG- produzida no figado

(Não confundir com tireoglobulina)

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3
Q

T4 é transformado em T3 através da:

A

Deiodinase 1 e 2

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4
Q

Função da deiodinase 3

A

Transforma T4 em T3r

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5
Q

JOD basedow

vs

Wolf-Chaikoff

A

JOD = JOB = excesso de iodo leva a hipertireoidismo

Wolf-ChaikOFF = excesso de iodo leva a hipotireoidismo

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6
Q

Principais hormônios pedidos para avaliar função tireoidiana:

A

T4l e TSH

T3 total

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7
Q

Sindrome do eutireoideo doente, o que é?

A

T3 baixo

deiodinase 3 ativa- maior T3r

TBG baixa

Aumento da Deiodinase 2- TSH abaixa

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8
Q

Situações que aumentam T4 total, mas T4 livre continua normal:

A

hepatite e anticoncepcional

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9
Q

Principal droga relacionada à JOD basedow e wolff chackoff:

A

amiodarona

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10
Q

Valores normais de T4 em adultos:

A

0.7 a 1.8 ng/dl

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11
Q

Valores normais de TSH em adultos:

A

0,3 a 4,0 mUI/L

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