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Step 1 Memorization Hour > Toxicities + Antidotes > Flashcards

Toxicities + Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetyl cysteine (replenish glutathione)

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2
Q

Cholinesterase or Organophosphate

A

Atropine (pralidoxine if early to inc cholinesterases)

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3
Q

Antimuscarinics or Anticholinergics (atropine)

A

Physostigmine (CNS penetration), control their hyperthermia

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4
Q

Arsenic

A

Dimercaprol, succimer

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5
Q

Benzodiazepines

A

Flumazenil (comp antagonist at GABA)

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6
Q

Beta Blockers

A

atropine, glucagon

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7
Q

Carbon Monoxide

A

100% oxygen or hyperbaric oxygen

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8
Q

Copper

A

Penicillamine (penny), trientine

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9
Q

Cyanide

A

Nitrite + thiosulfate, hydroxocobalamin

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10
Q

Digoxin

A

Anti-dig Fab fragments

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11
Q

Heparin

A

Protamine sulfate

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12
Q

Iron

A

DeFEroxamine, deFErasirox, deFeriprone

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13
Q

Lead

A

EDTA

Dimercaprol, succimer (same as arsenic)

Penicillamine (same as copper)

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14
Q

Mercury

A

DiMERcarpol, succiMER (same as arsenic and lead)

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15
Q

Methanol, ethylene glycol

A

Fomepizole (alcohol DH inhibitor), dialysis

Ethanol

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16
Q

Methemoglobin

A

Methylene blue (Fe from 3 to 2)

Vit C

17
Q

Opioids

A

Naloxone

18
Q

Salicylates

A

Weak acid so trap by alkalizing urine (sodium bicarbonate)

19
Q

TCAs

A

Weak base so trap by acidifying urine (ammonium Cl)

20
Q

Warfarin

A

Fresh frozen plasma immediately

Vit K (delayed effect)

Step 1 Memorization Hour (127 decks)

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