Rate Limiting Steps Flashcards

1
Q

Glycolysis

A

PFK-1

activated when insulin dec cAMP so protein kinase A inactive - favors PFK2

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2
Q

Gluconeogenesis

A

Fructose - 1,6 bisphosphate

When fasting glucagon inc cAMP to inc protein kinase A - favors fructose bisphosphatase 2

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3
Q

TCA Cycle

A

Isocitrate DH

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4
Q

Glycogenesis

A

Glycogen synthase

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5
Q

Glycogenolysis

A

Glycogen phosphorylase

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6
Q

HMP Shunt

A

Gluc- 6- phos DH (G6PD)

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7
Q

De Novo Pyrimidine Synthesis

A

Carbomyl Phos Synthetase II

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8
Q

De Novo Purine Synthesis

A

Glutamine - PRPP - amidotransferase

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9
Q

Urea Cycle

A

Carbomyl Phos Synthetase I

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10
Q

FA Synthesis

A

Acetyl CoA Carboxylase

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11
Q

Ketogenesis

A

HMG CoA Synthase

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12
Q

Cholesterol Synthesis

A

HMG CoA Reductase

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