Brain Lesions

Question 1

Frontal Lobe Lesion

Answer 1

• Disinhibition, dec concentration, dec judgement, dec orientation
• May have re-emergence of primitive reflexes

Question 2

Frontal Eye Field Lesion

Answer 2

Eyes look toward lesion

Question 3

Paramedian Pontine Reticular Formation Lesion

Answer 3

Eyes look away from lesion

Question 4

MLF Lesion

Answer 4

• Seen in MS
• Internuclear opthalmalagia
• Impaired adduction of ipsilateral eye & nystagmus of contralateral eye when try to abduct it

Question 5

Dominant Parietal Lesion

Answer 5

Agraphia, acalculia, finger agnosia, L-R disorientation

Gerstmann Syndrome

Question 6

Non-dominant Parietal Lesion

Answer 6

Hemispatial Neglect (of contralateral side)

Question 7

Bilateral Hippocampus Lesion

Answer 7

Anterograde amnesia (no new memories)

Question 8

BG Lesion

Answer 8

Resting tremor, chorea, athetosis

Question 9

Subthalamic Nucleus Lesion

Answer 9

Contralateral hemi-ballismus

Question 10

Bilateral Mammilary Body Lesion

Answer 10

Wernicke-Korsakoff Syndrome

-CAN’O beer

C - confusion
A - ataxia
N - nystagmus
O - opthalmoplegia

+ confabulation, personality changes, amnesia

Question 11

Bilateral Amygdala Lesion

Answer 11

Kluver-Bucy Syndrome

• HSV-1 encephalitis
• disinhibition (inc talking, inc sexuality)

Question 12

Superior Colliculus Lesion

Answer 12

Parinaud Syndrome

-paralysis of conjugate vertical gaze

Question 13

Midbrain Lesion

Answer 13

-If reticular activating system then reduced arousal and wakefullness (coma)

Question 14

Cerebellar Hemisphere Lesion

Answer 14

Intention tremor, limb ataxia, loss of balance

Fall toward side of lesion

IPSILATERAL

Question 15

Cerebellar Vermis Lesion

Answer 15

Vermis is central - affects central body (truncal ataxia and dysarthria)

-Seen in chronic alcohol use